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Identification and analysis of tumour-associated antigens in hepatocellular carcinoma
To identify tumour and tumour-associated antigens in patients with hepatocellular carcinoma (HCC) one may find potential diagnostic markers and immunotherapeutic targets. In the current study, 30… Expand
TSPY is a cancer testis antigen expressed in human hepatocellular carcinoma
In search for genes associated with hepatocellular carcinoma (HCC) by cDNA microarray, we found that the transcription of TSPY, ‘testis-specific protein Y-encoded’, was upregulated in HCC.… Expand
Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P‐p38 mitogen‐activated protein kinase activation in streptozotocin‐induced diabetic rats
In experimental early painful diabetic neuropathy, persistent hyperglycaemia induces dys‐regulated sodium channel (Navs) expression in the dorsal root ganglion (DRG) and activates microglia in the… Expand
2-hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid with inbuilt β-N-hydroxy-γ-keto-acid pharmacophore as HCV NS5B polymerase inhibitors.
- R. Deore, G. S. Chen, +5 authors J-W Chern
- Biology, Medicine
- Current medicinal chemistry
- 31 January 2012
The inbuilt 2-N-hydroxy-1-oxo-3-carboxylic acid of isoquinolone was designed as pyrophosphate mimic for hepatitis C NS5B polymerase. Various 2-hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid… Expand
Effects of metoprolol and small intestine RNA on marrow-derived endothelial progenitor cells applied for autograft transplantation in heart disease.
- K. Cheng, M. Wei, +6 authors X. Zhou
- Biology, Medicine
- European review for medical and pharmacological…
- 1 June 2014
AIMS The objective of this project was to improve the effect of EPC autograft transplantation and observe the tolerance of EPCs to I/R injury affected by metoprolol and small intestine RNA. … Expand
Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)
Crystal Structure of hypothetical transcription factor NHTF from Neisseria