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Molecular Characterization of Chronic Obstructive Pulmonary Disease-Related Non-Small Cell Lung Cancer Through Aberrant Methylation and Alterations of EGFR Signaling
BackgroundThe aim of this study was to evaluate the molecular influence of chronic obstructive pulmonary diseases (COPD) on the pathogenesis of non-small cell lung cancer (NSCLC).Materials andExpand
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Prosthetic reconstruction of the superior vena cava for malignant disease: surgical techniques and outcomes.
BACKGROUND This retrospective study investigated long-term graft patency and outcomes for malignant diseases with invasion of the superior vena cava (SVC). METHODS From October 1995 to NovemberExpand
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Thoracoscopic ultrasonography for localization of subcentimetre lung nodules.
OBJECTIVES Localization of small, non-visible and non-palpable subcentimetre nodules can be challenging during video-assisted thoracoscopic surgery (VATS). Intraoperative ultrasonography is an optionExpand
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Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis.
Several studies have described p16INK4A and prostaglandin E2 (PGE2) co-alterations in various solid tumors, including non-small cell lung cancer (NSCLC). In this study, we examined the correlationExpand
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A novel minimally invasive near‐infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial
Objectives Localization and resection of nonvisible, nonpalpable pulmonary nodules during video‐assisted thoracoscopic surgery are challenging. Our study was to determine the feasibility and safetyExpand
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Lymph node staging by endobronchial ultrasound-guided transbronchial needle aspiration in patients with small cell lung cancer.
BACKGROUND Surgical treatment of small cell lung cancer (SCLC) is limited to stage I disease. Therefore, accurate lymph node staging is mandatory in SCLC patients. The purpose of this study was toExpand
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Transplantation of alveolar type II cells stimulates lung regeneration during compensatory lung growth in adult rats.
OBJECTIVE It is controversial whether lung regeneration contributes to compensatory lung growth after pulmonary resection in mature individuals. The objectives of this study were to clarify theExpand
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SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma.
Malignant pleural mesothelioma (MPM) is an aggressive type of cancer of the thoracic cavity commonly associated with asbestos exposure and a high mortality rate. There is a need for new molecularExpand
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Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs.
BACKGROUND Localization of small, nonvisible and nonpalpable nodules is challenging during video-assisted thoracoscopic surgery. We evaluated the feasibility of using a new ultrasound thoracoscope toExpand
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Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma
Photodynamic therapy (PDT) following lung- sparing extended pleurectomy for malignant pleural mesothelioma (MPM) has been investigated as a potential means to kill residual microscopic cells. HighExpand
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