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RET, ROS1 and ALK fusions in lung cancer
TLDR
A multivariate analysis of 1,116 adenocarcinomas containing 71 kinase-fusion–positive adenokcinomas identified four independent factors that are indicators of poor prognosis: age ≥50 years, male sex, high pathological stage and negative kinase -fusion status. Expand
Incidence of urethral stricture after bipolar transurethral resection of the prostate using TURis: results from a randomised trial
To assess whether bipolar transurethral resection of the prostate (B‐TURP) using the TURis® system has a similar level of efficacy and safety to that of the traditional monopolar transurethralExpand
Could transurethral resection of the prostate using the TURis system take over conventional monopolar transurethral resection of the prostate? A randomized controlled trial and midterm results.
TLDR
The TURis system required significantly more resection time, which might not entirely be a panacea for the treatment of benign prostatic obstruction, especially for patients having larger prostatic volumes. Expand
Over-expression of E2F-1 in esophageal squamous cell carcinoma correlates with tumor progression.
TLDR
Over-expression of E2F-1 is associated with tumor progression and a worse prognosis after surgery in ESCC, and the overall survival rate was worse in patients with E2f-1-positive tumors than in Patients with E 2F- 1-negative tumors. Expand
Pulmonary function after segmentectomy for small peripheral carcinoma of the lung.
TLDR
Pulmonary function after a segmentectomy for a good-risk patient is slightly better than that after a lobectomy, however, segmentectomy should be still the surgical procedure for only poor-risk patients because of the difficulty in excluding patients with metastatic lymph nodes from the candidates for the procedure. Expand
Prognostic role of positron emission tomography and high-resolution computed tomography in clinical stage IA lung adenocarcinoma.
TLDR
The combination of maxSUV and GGO ratio as well as each alone are important predictors of prognosis in patients with clinical stage IA adenocarcinoma of the lung and should be considered before selecting therapeutic strategies. Expand
Frailty and Transplantation
TLDR
A risk assessment of frailty at the time of transplant evaluation and review effects on outcomes and recovery after transplantation is provided and the current understanding of the pathophysiology of frailt and consequences on immune responses and metabolism is summarized. Expand
microRNA-145 Mediates the Inhibitory Effect of Adipose Tissue-Derived Stromal Cells on Prostate Cancer.
TLDR
Preclinical data is provided that ASCs inhibit PCa growth, inducing PCa cell apoptosis with reduced activity of BclxL, at least in part, by miR-145, including exosomes released from ASCs, suggesting that ASC administration could be a novel and promising therapeutic strategy in patients with PCa. Expand
Expression of Pigment Epithelium-Derived Factor Decreases Liver Metastasis and Correlates with Favorable Prognosis for Patients with Ductal Pancreatic Adenocarcinoma
TLDR
Pigment epithelium-derived factor expression suggests a more favorable prognosis than in patients whose carcinomas lack PEDF expression, according to the risk ratio. Expand
Value of integrated positron emission tomography revised using a phantom study to evaluate malignancy grade of lung adenocarcinoma
TLDR
The authors evaluated malignancy grades of small adenocarcinomas using fluorodeoxyglucose‐positron emission tomography/computed tomography (PET/CT) in addition to high‐resolution CT (HRCT) and pathological analysis in a multicenter setting. Expand
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