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Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus.
Differently substituted flavanones were isolated from Leguminosae and their antibacterial activity was comparatively studied against methicillin-resistant Staphylococcus aureus (MRSA). The minimumExpand
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Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system.
Ion-channel beta-subunits are ancillary proteins that co-assemble with alpha-subunits to modulate gating kinetics and enhance stability of multimeric channel complexes. They provide binding sites forExpand
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Leaching and cytotoxicity of formaldehyde and methyl methacrylate from acrylic resin denture base materials.
Acrylic resin dentures have the potential to elicit irritation, inflammation, and an allergic response of the oral mucosa. Studies of substances leachable from acrylic resins, their cytotoxicity toExpand
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Flavones with antibacterial activity against cariogenic bacteria.
Methanolic extracts obtained from 13 plants were studied for their antibacterial activity against cariogenic bacteria. Among them, the extract from Artocarpus heterophyllus showed the most intensiveExpand
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Membrane‐rigidifying effects of anti‐cancer dietary factors
Since several anti‐cancer drugs interact with cell membrane lipids, the effects of anti‐cancer dietary factors on liposomal membranes with different lipid composition were comparatively studied byExpand
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Membrane Interactions of Phytochemicals as Their Molecular Mechanism Applicable to the Discovery of Drug Leads from Plants
In addition to interacting with functional proteins such as receptors, ion channels, and enzymes, a variety of drugs mechanistically act on membrane lipids to change the physicochemical properties ofExpand
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Structure-dependent membrane interaction of flavonoids associated with their bioactivity
Abstract Plant foods contain various flavonoids with nutraceutical and health benefits. Structurally different flavonoids were compared by the potency to interact with liposomal membranes in theExpand
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Structure‐Specific Membrane‐Fluidizing Effect Of Propofol
  • H. Tsuchiya
  • Chemistry, Medicine
  • Clinical and experimental pharmacology…
  • 1 April 2001
1. While recent studies about the pharmacological mechanism of the intravenous anaesthetic propofol (2,6‐diisopropylphenol) have focused on its interaction with functional proteins, there is theExpand
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Biphasic membrane effects of capsaicin, an active component in Capsicum species.
  • H. Tsuchiya
  • Chemistry, Medicine
  • Journal of ethnopharmacology
  • 1 May 2001
Capsaicin, an active component in Capsicum species, not only stimulates sensory afferent neurons but also inhibits bacterial growth and platelet aggregation. To address the pharmacological mechanismExpand
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  • PDF
Antiplatelet activity of soy sauce as functional seasoning.
In seeking the functionality of foodstuffs applicable to medicine, soy sauce was found to show antiplatelet activity. Therefore, the active components in soy sauce were purified, structurallyExpand
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