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Electrophysiologic activity and antiarrhythmic efficacy of CK-3579, a new class III antiarrhythmic agent with beta-adrenergic blocking properties.
- T. Argentieri, H. Troy, M. S. Carroll, C. M. Doroshuk, M. Sullivan
- Journal of cardiovascular pharmacology
- 1 April 1993
CK-3579 (N-[4-[2-hydroxy-3-[[2-[4-(1H-inidazol-1- yl)phenoxy]ethyl]amino]propoxy]phenyl]methanesulfonamide, HCL-[RS]), is a new class III antiarrhythmic agent with beta-adrenoceptor blocking… Expand
The thiazolidinedione peroxisome proliferator-activated receptor gamma (PPARγ) agonist troglitazone alters histone post-translational modifications in MCF7 breast cancer cells.
Abstract #2140 Troglitazone (TRG), a thiazolidinedione (TZD) PPARγ ligand, is a potent antiproliferative agent in many different cancer cell lines. We have previously demonstrated in multiple drug… Expand