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Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.
Polymorphisms in DNA repair genes may be associated with differences in DNA repair capacity, thereby influencing the individual susceptibility to smoking-related cancer. We investigated the… Expand
Patient-Specific Dose and Radiation Risk Estimation in Pediatric Cardiac Catheterization
Background—Because of the higher radiosensitivity of infants and children compared with adults, there is a need to evaluate the doses delivered to pediatric patients who undergo interventional… Expand
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure.
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field… Expand
Optimised tracer-dependent dosage cards to obtain weight-independent effective doses
- F. Jacobs, H. Thierens, +4 authors R. Dierckx
- European Journal of Nuclear Medicine and…
- 1 May 2005
PurposeThe aim of this study was twofold: firstly, to determine whether the European Association of Nuclear Medicine (EANM) dosage card results in weight-independent effective doses or… Expand
Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer.
- I. Madani, W. Duthoy, +12 authors W. De Neve
- International journal of radiation oncology…
- 1 May 2007
PURPOSE To assess the feasibility of intensity-modulated radiotherapy (IMRT) using positron emission tomography (PET)-guided dose escalation, and to determine the maximum tolerated dose in head and… Expand
The micronucleus assay in radiation accidents.
The cytokinesis-block micronucleus assay in peripheral blood lymphocytes is a standardised and validated technique for biodosimetry. Automated scoring of micronuclei allows large scale applications… Expand
Correlation of patient skin doses in cardiac interventional radiology with dose-area product.
- S. van de Putte, F. Verhaegen, Y. Taeymans, H. Thierens
- The British journal of radiology
- 1 May 2000
The use of X-rays in cardiac interventional radiology has the potential to induce deterministic radiation effects on the patient's skin. Guidelines published by official organizations encourage the… Expand
Single-nucleotide polymorphisms in DNA double-strand break repair genes: association with head and neck cancer and interaction with tobacco use and alcohol consumption.
We investigated the effect of different levels of smoking and drinking on the development of squamous cell carcinoma of head and neck (HNSCC) and performed analyses to evaluate possible differences… Expand
Cytogenetic monitoring of hospital workers occupationally exposed to ionizing radiation using the micronucleus centromere assay.
A cytogenetic study was performed in lymphocytes of hospital workers occupationally exposed to X- and gamma-rays using the micronucleus centromere assay. A comparison of the data for the exposed… Expand
Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations.
- B. Vanderstraeten, N. Reynaert, +5 authors H. Thierens
- Mathematics, Medicine
- Medical physics
- 1 September 2006
The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with… Expand