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Diabetes and risk of pancreatic cancer: a pooled analysis of three large case–control studies
- D. Li, H. Tang, M. Hassan, E. Holly, P. Bracci, D. Silverman
- Cancer Causes & Control
- 1 February 2011
Racial differences in diabetes-associated pancreatic cancer (PC) and the interaction of diabetes with other risk factors are not well established. We determined the association between diabetes and… Expand
Body Mass Index and Obesity- and Diabetes-Associated Genotypes and Risk for Pancreatic Cancer
- H. Tang, Xiaoqun Dong, M. Hassan, J. Abbruzzese, D. Li
- Cancer Epidemiology, Biomarkers & Prevention
- 25 February 2011
Background: The genetic factors predisposing individuals with obesity or diabetes to pancreatic cancer have not been identified. Aims: To investigate the hypothesis that obesity- and diabetes-related… Expand
Expressions and clinical significances of angiopoietin-1, -2 and Tie2 in human gastric cancer.
- J. Wang, Kaichun Wu, +8 authors D. Fan
- Biology, Medicine
- Biochemical and biophysical research…
- 11 November 2005
The roles of angiopoietins in gastric cancer progression are still not fully understood. In this study the expressions of angiopoietin-1 (Ang-1), -2 (Ang-2) were compared by immunohistochemistry in… Expand
Insights into Pancreatic Cancer Etiology from Pathway Analysis of Genome-Wide Association Study Data
Background Pancreatic cancer is the fourth leading cause of cancer death in the U.S. and the etiology of this highly lethal disease has not been well defined. To identify genetic susceptibility… Expand
Antioxidant genes, diabetes and dietary antioxidants in association with risk of pancreatic cancer.
To test the hypothesis that polymorphic variants of antioxidant genes modify the risk of pancreatic cancer, we examined seven single-nucleotide polymorphisms (SNPs) of genes coding for superoxide… Expand
Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.
OBJECTIVE Insulin-like growth factor (IGF)-axis genes plays a critical role in cancer development and progression via their impact on the RAS/MAPK/ERK and PI3K/AKT/mTOR signaling pathways. We… Expand
Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p
Growing evidences indicated that Long noncoding RNAs (lncRNAs) played important roles in tumor initiation and progression. However, the function and mechnism of lncRNA ferritin heavy chain 1… Expand
Inhibition of osteopontin would suppress angiogenesis in gastric cancer.
- H. Tang, J. Wang, +8 authors D. Fan
- Biology, Medicine
- Biochemistry and cell biology = Biochimie et…
- 21 February 2007
Osteopontin (OPN) plays an important role in tumorigenesis, tumor invasion, and metastasis in many types of cancers, including gastric cancer. Recently, much interest has been focused on the role of… Expand
Axonal guidance signaling pathway interacting with smoking in modifying the risk of pancreatic cancer: a gene- and pathway-based interaction analysis of GWAS data.
Cigarette smoking is the best established modifiable risk factor for pancreatic cancer. Genetic factors that underlie smoking-related pancreatic cancer have previously not been examined at the… Expand
Three-point bending fatigue behavior of WC–Co cemented carbides
Abstract WC–Co cemented carbides with different WC grain sizes and Co binder contents were sintered and fabricated. The three-point bending specimens with a single edge notch were prepared for tests.… Expand