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Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. PhylogeneticExpand
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Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris.
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organismExpand
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MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin.
MicroRNAs (miRNAs) may function as oncogenes or tumor suppressors. Here, we show that miR-27a is up-regulated in human gastric adenocarcinoma. Suppression of miR-27a inhibits gastric cancer cellExpand
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MicroRNA‐9 inhibits ovarian cancer cell growth through regulation of NF‐κB1
MicroRNAs are emerging as important regulators of cancer‐related processes. Our studies show that microRNA‐9 (miR‐9) is downregulated in human ovarian cancer relative to normal ovary, andExpand
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Genetic Architecture of Skin and Eye Color in an African-European Admixed Population
Variation in human skin and eye color is substantial and especially apparent in admixed populations, yet the underlying genetic architecture is poorly understood because most genome-wide studies areExpand
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Transduction of Growth or Mitogenic Signals into Translational Activation of TOP mRNAs Is Fully Reliant on the Phosphatidylinositol 3-Kinase-Mediated Pathway but Requires neither S6K1 nor rpS6
ABSTRACT Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now showExpand
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miR-490-3p Modulates Cell Growth and Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma Cells by Targeting Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3 (ERGIC3)*
Background: The role of miR-490-3p in hepatocellular carcinoma (HCC) has not been well clarified. Results: miR-490-3p is up-regulated in HCC and enhances the cell proliferation, migration, invasionExpand
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The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication.
The extent of molecular differentiation between domesticated animals or plants and their wild relatives is postulated to be small. The availability of the complete genome sequences of two subspeciesExpand
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Genetic admixture and asthma‐related phenotypes in Mexican American and Puerto Rican asthmatics
Genetic association studies in admixed populations may be biased if individual ancestry varies within the population and the phenotype of interest is associated with ancestry. However, recentlyExpand
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Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells.
  • R. Qiang, F. Wang, +8 authors H. Tang
  • Biology, Medicine
  • The international journal of biochemistry & cell…
  • 1 April 2011
Plexin-B1, the receptor for Sema4D, has been reported to trigger multiple and sometimes opposing cellular responses in various types of tumor cells. It has been implicated in the regulation ofExpand
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