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Rapid killing of human neutrophils by the potent activator phorbol 12‐myristate 13‐acetate (PMA) accompanied by changes different from typical apoptosis or necrosis
To elucidate the relationship between activation of neutrophils and their subsequent death, the effect of phorbol 12‐myristate 13‐acetate (PMA), a potent activator of neutrophils, was examined.Expand
The cytotoxic effect of titanium particles phagocytosed by osteoblasts.
The cytotoxic effect of different concentrations of titanium particles on osteoblasts was studied in vitro. It was found that the viability of the osteoblasts was inversely proportional to theExpand
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system.
Human thioredoxin (hTrx), a small ubiquitous protein with strong reducing potential, has multiple biological functions, including signal transduction and regulation of the activity of transcriptionExpand
Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles.
Particles generated from orthopedic implants through years of wear play an essential role in the aseptic loosening of a prosthesis. We have investigated the biocompatibility of these orthopedicExpand
A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: a possible role for regulation of neutrophil adherence and migration.
We report here a novel glycosylphosphatidyl-inositol (GPI)-anchored glycoprotein on human leukocytes. Treatment of neutrophils with a mAb (3H9) to this molecule sequentially up-regulates andExpand
Absence of Biglycan Accelerates the Degenerative Process in Mouse Intervertebral Disc
Study Design. A study of the histologic changes of the intervertebral discs (IVDs) in biglycan (Bgn)-deficient mice. Objective. In this study, we investigate whether the absence of Bgn acceleratesExpand
The primary structure of adult hemoglobin from Macaca mulatta moneky.
The effects of calcium phosphate cement particles on osteoblast functions.
Calcium phosphate cements (CPC) are increasingly used in the orthopedic field. This kind of cement has potential applications in bone defect replacements, osteosynthetic screw reinforcements or drugExpand
In vivo regulation of rat neutrophil apoptosis occurring spontaneously or induced with TNF-alpha or cycloheximide.
We previously demonstrated that human TNF-alpha induces rapid apoptosis of human neutrophils. To understand better the in vivo significance of neutrophil apoptosis, we examined spontaneous,Expand
Combined effect of titanium particles and TNF-alpha on the production of IL-6 by osteoblast-like cells.
To clarify the role of tumor necrosis factor (TNF)-alpha on osteoblast functions in the presence of metal particles, two human osteoblast-like cell lines (MG-63 and SaOS-2) were cultured withExpand