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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.
- H. Takayanagi, Sunhwa Kim, T. Taniguchi
- BiologyDevelopmental cell
- 1 December 2002
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems
- H. Takayanagi
- BiologyNature Reviews Immunology
- 1 April 2007
TLDR
The molecular understanding of osteoclast differentiation.
- M. Asagiri, H. Takayanagi
- BiologyBone
- 1 February 2007
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
TLDR
Evidence for osteocyte regulation of bone homeostasis through RANKL expression
- T. Nakashima, M. Hayashi, H. Takayanagi
- Biology, MedicineNature Medicine
- 1 October 2011
TLDR
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
- H. Takayanagi, Sunhwa Kim, T. Taniguchi
- Biology, MedicineNature
- 18 April 2002
TLDR
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
- Kojiro Sato, A. Suematsu, H. Takayanagi
- Biology, MedicineThe Journal of experimental medicine
- 27 November 2006
TLDR
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
- N. Komatsu, Kazuo Okamoto, H. Takayanagi
- Biology, MedicineNature Medicine
- 1 January 2014
TLDR
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
- M. Asagiri, Kojiro Sato, H. Takayanagi
- BiologyThe Journal of experimental medicine
- 7 November 2005
TLDR
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.
- H. Takayanagi, K. Ogasawara, T. Taniguchi
- Biology, MedicineNature
- 2000
TLDR
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