Cloning and Characterization of a Streptomyces Single Module Type Non-ribosomal Peptide Synthetase Catalyzing a Blue Pigment Synthesis*
- H. Takahashi, T. Kumagai, K. Kitani, M. Mori, Y. Matoba, M. Sugiyama
- Biology, ChemistryJournal of Biological Chemistry
- 23 March 2007
Each site-directed mutagenesis experiment of Lys598, Tyr601, Ser603, and Tyr608, which are seen in the oxidation domain of BPSA, suggests that these residues are essential for the binding of FMN to the protein and the synthesis of the blue pigment.
Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus.
- Y. Tsuda, H. Takahashi, Makiko Kobayashi, T. Hanafusa, D. Herndon, F. Suzuki
- BiologyImmunity
- 1 August 2004
Molecular Cloning of the Family of Glutamine Synthetase Genes from Maize: Expression of Genes for Glutamine Synthetase and Ferredoxin-Dependent Glutamate Synthase in Photosynthetic and…
- H. Sakakibara, S. Kawabata, H. Takahashi, T. Hase, T. Sugiyama
- Biology
- 1992
Water penetration into rice grains during soaking observed by gradient echo magnetic resonance imaging
- A. Horigane, H. Takahashi, S. Maruyama, K. Ohtsubo, Mitsuru Yoshida
- Materials Science
- 1 November 2006
Elastic theory of supercoiled DNA
- F. Tanaka, H. Takahashi
- Engineering
- 1 December 1985
This paper estimates the configurational energies of a closed DNA molecule in highly supercoiled states. Calculation is based on an elastic rod model characterized by the bending and torsional…
Age-dependent vulnerability to endotoxemia is associated with reduction of anticoagulant factors activated protein C and thrombomodulin.
- M. Starr, Junji Ueda, H. Saito
- Medicine, BiologyBlood
- 10 June 2010
It is demonstrated that PC pathway activation is suppressed with aging and is partly responsible for age-associated thrombosis and high mortality during endotoxemia in mice.
Decreased pulmonary extracellular superoxide dismutase during systemic inflammation.
- Junji Ueda, M. Starr, H. Saito
- BiologyFree Radical Biology & Medicine
- 15 September 2008
An essential role of macrophage inflammatory protein 1α/CCL3 on the expression of host’s innate immunities against infectious complications
- H. Takahashi, T. Tashiro, M. Miyazaki, Makiko Kobayashi, R. Pollard, F. Suzuki
- BiologyJournal of Leukocyte Biology
- 1 December 2002
Macrophages but not neutrophils are highlighted as the major effector cells when protective innate immunities against sepsis are improved by CCL3, shown to be essential to the host resistance against bacterial sepsi.
CCL2 as a trigger of manifestations of compensatory anti‐inflammatory response syndrome in mice with severe systemic inflammatory response syndrome
- H. Takahashi, Y. Tsuda, Makiko Kobayashi, D. Herndon, F. Suzuki
- Biology, MedicineJournal of Leukocyte Biology
- 1 April 2006
Results indicate that CCL2 produced by PMN from SIRS mice is an active molecule on the SirS‐associated CARS manifestation.
Plasmodiophora brassicae-induced cell death and medium alkalization in clubroot-resistant cultured roots of Brassica rapa.
- H. Takahashi, T. Ishikawa, H. Hori
- Biology
- 1 March 2006
The results suggest the involvement of Ca2+ in P. brassicae-induced cell death and conclude that the root culture system must be a useful tool for further studies of the molecular mechanism of clubroot resistance.
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