H. Szechtman

Publications182
h-index50
Citations8,410
Highly Influential Citations244
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Obsessive-compulsive disorder as a disturbance of security motivation.
TLDR
The authors compare their satiety-signal construct, which they term yedasentience, to various other senses of the feeling of knowing and indicate why OCD-like symptoms would stem from the abnormal absence of such a terminator emotion.
Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD).
TLDR
An animal model of obsessive-compulsive disorder and a role for dopamine in this disorder is suggested and Quinpirole-induced compulsive checking may be an exaggeration of normal checking of home site in rats.
Biphasic effect of D-2 agonist quinpirole on locomotion and movements.
Psychosis pathways converge via D2High dopamine receptors
TLDR
The evidence suggests that there are multiple pathways that convergetoelevate the D2High state in brain regions and that this elevation may elicit psychosis.
Where the imaginal appears real: a positron emission tomography study of auditory hallucinations.
TLDR
Inappropriate activation of the right anterior cingulate may lead self-generated thoughts to be experienced as external, producing spontaneous auditory hallucinations.
Enhanced salience and emotion recognition in Autism: a PET study.
TLDR
It is suggested that the recognition of emotion by adults with autism is achieved through recruitment of brain regions concerned with allocation of attention, sensory gating, the referencing of perceptual knowledge, and categorization.
Synchrony among rhythmical facial tremor, neocortical ‘ALPHA’ waves, and thalamic non-sensory neuronal bursts in intact awake rats
Quinpirole induces compulsive checking behavior in rats: A potential animal model of obsessive-compulsive disorder (OCD).
TLDR
An animal model of obsessive-compulsive disorder and a role for dopamine in this disorder is suggested and Quinpiroleinduced compulsive checking may be an exaggeration of normal checking of home site in rats.
Adaptation to potential threat: The evolution, neurobiology, and psychopathology of the security motivation system
Disturbed emotionality in autoimmune MRL-lpr mice
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