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Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase.
BACKGROUND  Chronic alcohol consumption increases ischemic stroke and exacerbates ischemic brain injury. We determined the role of NAD(P)H oxidase in exacerbated ischemic brain injury during chronicExpand
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Influence of exercise training on ischemic brain injury in type 1 diabetic rats.
While exercise training (ExT) appears to influence cerebrovascular function during type 1 diabetes (T1D), it is not clear whether this beneficial effect extends to protecting the brain fromExpand
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Temporal effect of alcohol consumption on reactivity of pial arterioles: role of oxygen radicals.
  • H. Sun, W. Mayhan
  • Chemistry, Medicine
  • American journal of physiology. Heart and…
  • 1 March 2001
Chronic alcohol consumption reduces nitric oxide synthase-dependent responses of pial arterioles via mechanisms that remain uncertain. In addition, the temporal effects of alcohol on pial arteriolesExpand
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In vitro inhibition of Ras-Raf association by short peptides.
Seven amino acid peptides were tested as in vitro inhibitors of oncogenic Ras-Raf association. The sequences of these peptides were derived from the H-Ras effector region (amino acids 25 to 51) andExpand
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A modified suture technique produces consistent cerebral infarction in rats
Intraluminal occlusion of the middle cerebral artery (MCA) is used extensively in cerebral ischemia research. We tested a modified nylon suture in a rat model of middle cerebral artery occlusionExpand
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Cytokine Mrna Profiles In Mouse Orthotopic Liver Transplantation Graft Rejectionis Associasted With Augmented Th1 Function
Although mouse liver allografts are spontaneously accepted without immunosuppression in many strain combinations, rejection can be induced by presensitization with a donor skin graft two weeks priorExpand
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Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice.
The multidrug resistant-associated protein 1 (MRP1) is a membrane-bound transport protein that is involved in the efflux of organic anions and has been implicated in multidrug resistance in cancer.Expand
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Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain.
Intracerebral microdialysis probe recovery (extraction fraction) may be influenced by several mass transport processes in the brain, including efflux and uptake exchange between brain and blood.Expand
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Tetrahydrobiopterin, a cofactor for NOS, improves endothelial dysfunction during chronic alcohol consumption.
We sought to investigate mechanisms that may account for impaired nitric oxide synthase (NOS)-dependent dilatation of cerebral arterioles during alcohol consumption. Our goals were to examine 1) theExpand
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Impairment of neuronal nitric oxide synthase-dependent dilation of cerebral arterioles during chronic alcohol consumption.
BACKGROUND Although chronic alcohol consumption impairs endothelial nitric oxide synthase-dependent reactivity of cerebral arterioles, the effect of alcohol consumption on vasodilation in response toExpand
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