• Publications
  • Influence
Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice
Reelin, an extracellular glycoprotein has an important role in the proper migration and positioning of neurons during brain development. Lack of reelin causes not only disorganized lamination of theExpand
  • 28
  • 8
  • PDF
Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice
Amyotrophic lateral sclerosis (ALS) is a progressive disease which is caused by degeneration of motor neurons in the central nervous system. The incidence of ALS is higher in men than women, but theExpand
  • 82
  • 6
Id proteins facilitate self-renewal and proliferation of neural stem cells.
Members of helix-loop-helix (HLH) protein family of Id (inhibitor of differentiation) dimerize with bHLH transcription factors and function as negative regulators of differentiation duringExpand
  • 70
  • 6
Neural Induction with Neurogenin1 Increases the Therapeutic Effects of Mesenchymal Stem Cells in the Ischemic Brain
Mesenchymal stem cells (MSCs) have been shown to ameliorate a variety of neurological dysfunctions. This effect is believed to be mediated by their paracrine functions, since these cells rarelyExpand
  • 89
  • 5
  • PDF
cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK
Mesenchymal stem cells are able to trans-differentiate into nonmesodermal lineage cells. Here, we identified downstream signaling molecules required for acquisition of neuron-like traits byExpand
  • 60
  • 5
Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive
BackgroundContusive spinal cord injury is complicated by a delayed loss of oligodendrocytes, resulting in chronic progressive demyelination. Therefore, transplantation strategies to provideExpand
  • 81
  • 5
Expression of neuroD/BETA2 in mitotic and postmitotic neuronal cells during the development of nervous system
NeuroD/BETA2, a basic helix‐loop‐helix transcription factor, has been shown to play a role in tissue‐specific differentiation of pancreatic and enteroendocrine cells. To gain further insight into theExpand
  • 100
  • 4
Immunohistochemical study of central neurocytoma, subependymoma, and subependymal giant cell astrocytoma
SummaryFor investigation of histogenesis of central neurocytomas (CNs), subependymoma (SEs), subependymal giant cell astrocytomas (SEGAs), we studied expression of various neuronal and glialExpand
  • 55
  • 4
Immune following suppression mesenchymal stem cell transplantation in the ischemic brain is mediated by TGF-β
Transplantation of mesenchymal stem cells (MSCs) has been shown to enhance the recovery of brain functions following ischemic injury. Although immune modulation has been suggested to be one of theExpand
  • 84
  • 4
The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase
Suicide genes have recently emerged as an attractive alternative therapy for the treatment of various types of intractable cancers. The efficacy of suicide gene therapy relies on efficient geneExpand
  • 58
  • 4