• Publications
  • Influence
A census of mammalian imprinting.
Genomic imprinting, the parent-of-origin-specific silencing of a small proportion of genes, introduces a paradoxical vulnerability of hemizygosity into the diploid mammalian genome. To facilitate theExpand
  • 604
  • 32
  • PDF
Predictive adaptive responses and human evolution.
The importance of a single genotype being able to produce different phenotypes in different environments (phenotypic plasticity) is widely recognized in evolutionary theory and its adaptiveExpand
  • 545
  • 30
  • PDF
Metapopulation Structure Favors Plasticity over Local Adaptation
We describe a model for the evolutionary consequences of plasticity in an environmentally heterogeneous metapopulation in which specialists for each of two alternative environments and one plasticExpand
  • 538
  • 28
  • PDF
Kelp genes reveal effects of subantarctic sea ice during the Last Glacial Maximum
The end of the Last Glacial Maximum (LGM) dramatically reshaped temperate ecosystems, with many species moving poleward as temperatures rose and ice receded. Whereas reinvading terrestrial taxaExpand
  • 223
  • 26
  • PDF
Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies
Early experience has a particularly great effect on most organisms. Normal development may be disrupted by early environmental influences; individuals that survive have to cope with the damagingExpand
  • 347
  • 16
  • PDF
Contemporary habitat discontinuity and historic glacial ice drive genetic divergence in Chilean kelp
BackgroundSouth America's western coastline, extending in a near-straight line across some 35 latitudinal degrees, presents an elegant setting for assessing both contemporary and historic influencesExpand
  • 124
  • 16
  • PDF
Comparative and meta‐analytic insights into life extension via dietary restriction
Dietary restriction (DR) extends the lifespan of a wide range of species, although the universality of this effect has never been quantitatively examined. Here, we report the first comprehensiveExpand
  • 141
  • 11
HOW STABLE ‘SHOULD’ EPIGENETIC MODIFICATIONS BE? INSIGHTS FROM ADAPTIVE PLASTICITY AND BET HEDGING
Although there is keen interest in the potential adaptive value of epigenetic variation, it is unclear what conditions favor the stability of these variants either within or across generations.Expand
  • 126
  • 10
  • PDF
Circumpolar dispersal by rafting in two subantarctic kelp-dwelling crustaceans
Long-distance oceanic rafting is frequently invoked as an explanation for broad geographic distributions of sedentary marine taxa, but evidence for this ecological process remains elusive. WeExpand
  • 151
  • 10
  • PDF
The correlation between relatives on the supposition of genomic imprinting.
Standard genetic analyses assume that reciprocal heterozygotes are, on average, phenotypically identical. If a locus is subject to genomic imprinting, however, this assumption does not hold. WeExpand
  • 52
  • 9
  • PDF