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Surface micromachined capacitive ultrasonic transducers
A theoretical model is proposed that agrees well with observed transducer behavior and is used to demonstrate that microfabricated ultrasonic transducers constitute an attractive alternative to piezoelectric transducers in many applications. Expand
Synthesis of individual single-walled carbon nanotubes on patterned silicon wafers
Recent progress in the synthesis of high-quality single-walled carbon nanotubes (SWNTs) has enabled the measurement of their physical and materials properties. The idea that nanotubes might beExpand
Marker-specific sorting of rare cells using dielectrophoresis.
DACS offers the potential for automated, surface marker-specific cell sorting in a disposable format that is capable of simultaneously achieving high throughput, purity, and rare cell recovery. Expand
Multitarget magnetic activated cell sorter
The multitarget magnetic activated cell sorter (MT-MACS) is presented, which makes use of microfluidics technology to achieve simultaneous spatially-addressable sorting of multiple target cell types in a continuous-flow manner and has the capability to simultaneously sort multiple magnetic tags with >90% purity and >5,000-fold enrichment. Expand
Dielectrophoretic separation of platelets from diluted whole blood in microfluidic channels
This work demonstrates gentle and label‐free dielectrophoretic separation of delicate cells from complex samples and such a separation approach may open a path toward continuous screening of blood products by integrated microfluidic devices. Expand
Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor.
The approach of integrating folding-based electrochemical sensors with miniaturized detection systems may lay the groundwork for the real-time, point-of-care detection of a wide variety of molecular targets. Expand
Genetic analysis of H1N1 influenza virus from throat swab samples in a microfluidic system for point-of-care diagnostics.
The Magnetic Integrated Microfluidic Electrochemical Detector (MIMED) is presented that integrates sample preparation and electrochemical sensors in a monolithic disposable device to detect RNA-based virus directly from throat swab samples and demonstrates the detection of influenza H1N1 in throat swabs at loads as low as 10 TCID(50), 4 orders of magnitude below the clinical titer for this virus. Expand
MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers
MPBind, a Meta-motif-based statistical framework and pipeline to Predict the BIND: ing potential of SELEX-derived aptamers is presented and it was showed that MPBind is robust to both polymerase chain reaction amplification bias and incomplete sequencing of aptamer pools. Expand
Selection of mammalian cells based on their cell-cycle phase using dielectrophoresis
A microfluidic device that utilizes the dielectrophoresis phenomenon to synchronize cells by exploiting the relationship between the cell's volume and its phase in the cell cycle is reported. Expand
Particle display: a quantitative screening method for generating high-affinity aptamers.
An aptamer discovery technology that reproducibly yields higher affinity aptamers in fewer rounds compared to conventional selection is reported, and enrichment performance that exceeds the theoretical maximum achievable with conventional selection by many orders of magnitude is demonstrated. Expand