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A functional genomics approach toward the understanding of secondary metabolism in plant cells
Despite the tremendous importance of secondary metabolites for humans as for the plant itself, plant secondary metabolism remains poorly characterized. Here, we present an experimental approach,Expand
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Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria.
The differences in faecal bacterial population between irritable bowel syndrome (IBS) and control subjects have been reported in several studies. The aim of the present study was to compare theExpand
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A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E.
We describe a new technique by which single base changes in human genes can be conveniently detected. In this method the DNA fragment of interest is first amplified using the polymerase chainExpand
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Cellulose-binding domains promote hydrolysis of different sites on crystalline cellulose.
The cohesin-dockerin interaction in Clostridium thermocellum cellulosome mediates the tight binding of cellulolytic enzymes to the cellulosome-integrating protein CipA. Here, this interaction wasExpand
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Yeast protein translocation complex: Isolation of two genes SEB1 and SEB2 encoding proteins homologous to the Sec61β subunit
A yeast gene (cDNA clone) was isolated in a screen for suppressors of secretion‐defective sec15–1 mutation. This gene encodes a protein homologous to the β subunit of the mammalian Sec61 proteinExpand
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The β Subunit of the Sec61p Endoplasmic Reticulum Translocon Interacts with the Exocyst Complex in Saccharomyces cerevisiae*
The exocyst is a conserved protein complex proposed to mediate vesicle tethering at the plasma membrane. Previously, we identified SEB1/SBH1, encoding the β subunit of the Sec61p ER translocationExpand
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Amino acid sequence of alpha-amylase from Bacillus amyloliquefaciens deduced from the nucleotide sequence of the cloned gene.
We have isolated by molecular cloning the gene coding for the alpha-amylase (1,4-alpha-D-glucan glucanohydrolase, EC 3.2.1.1.) from Bacillus amyloliquefaciens and determined its complete nucleotideExpand
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Acetyl xylan esterase from Trichoderma reesei contains an active-site serine residue and a cellulose-binding domain.
The axe1 gene encoding acetyl xylan esterase was isolated from an expression library of the filamentous fungus Trichoderma reesei using antibodies raised against the purified enzyme. Apparently axe1Expand
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Transient Dimers of Allergens
Background Allergen-mediated cross-linking of IgE antibodies bound to the FcεRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, itsExpand
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Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen.
Allergies are caused by the immune reaction to commonly harmless proteins, allergens. This reaction is typified by immunoglobulin E (IgE) antibodies. We report the crystal structure of an IgE FabExpand
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