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Cancer Therapy–Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and Imaging
This review focuses on adult patients in all stages of cancer therapy from pretreatment surveillance, to ongoing therapy, and long-term follow-up, and concludes with a section on evidence gap and future directions.
Risk of Worsening Renal Function With Nesiritide in Patients With Acutely Decompensated Heart Failure
Nesiritide significantly increases the risk of worsening renal function in patients with acutely decompensated heart failure, and the prognostic importance of worsen renal function suggests the need for further investigation in appropriately powered clinical trials.
Central role for aldose reductase pathway in myocardial ischemic injury
- Y. Hwang, M. Kaneko, R. Ramasamy
- Biology, MedicineFASEB journal : official publication of the…
- 1 August 2004
Key roles for AR in ischemic injury and impairment of functional and metabolic recovery after ischemia are supported, and it is proposed that interventions targeting AR may provide a novel adjunctive approach to protect isChemic myocardium.
Embryonic expression of the Gax homeodomain protein in cardiac, smooth, and skeletal muscle.
Data suggest an important developmental role for Gax in all muscle lineages and homeobox-containing gene was detected in myotomes, premuscle masses, and mature muscle groups.
Noninvasive assessment and necropsy validation of changes in left ventricular mass in ascending aortic banded mice.
It is proposed that 2D echocardiography with a 12-MHz transducer is a powerful tool for serial noninvasive evaluations as an adjunct to the study of cardiac hypertrophy in the murine model.
Cancer Therapy–Related Cardiac Dysfunction and Heart Failure: Part 2: Prevention, Treatment, Guidelines, and Future Directions
This review discusses the epidemiologic, pathophysiological, risk factors, and imaging aspects of cancer therapy–related cardiac dysfunction and heart failure and concludes with highlighting the evidence gaps and future directions for research in this area.
Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.
In this pilot study of patients with nonischemic cardiomyopathy, itMSC therapy was safe, caused immunomodulatory effects, and was associated with improvements in health status and functional capacity.
High‐dose methylprednisolone in nonintubated patients with severe COVID‐19 pneumonia
- A. Papamanoli, Jeanwoo Yoo, A. Kalogeropoulos
- MedicineEuropean journal of clinical investigation
- 20 November 2020
Recent trials with dexamethasone and hydrocortisone have demonstrated benefit in patients with coronavirus disease 2019 (COVID‐19). Data on methylprednisolone are limited.
Hemodynamic profiles of ED patients with acute decompensated heart failure and their association with treatment.
Identification and characterization of a monoclonal antibody recognizing a galactose-binding domain of the toxin ricin.
- M. Colombatti, V. G. Johnson, H. Skopicki, B. Fendley, M. S. Lewis, R. Youle
- BiologyJournal of immunology
- 15 May 1987
In vivo, unlike lactose, the 75/3B12 antibody protected mice from ricin toxicity, and the antibody specificity indicates that structural differences exist in the galactose-binding sites of the Ricinus communis lectins.