• Publications
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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Neutrophil apoptosis pathways and their modifications in inflammation
  • H. Simon
  • Medicine, Biology
  • Immunological reviews
  • 1 June 2003
Summary:  Neutrophils are constantly produced in large numbers in the bone marrow, and the same numbers of cells need to die within a defined time period in order to keep cellular homeostasis underExpand
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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise isExpand
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Life and death partners: apoptosis, autophagy and the cross-talk between them
It is not surprising that the demise of a cell is a complex well-controlled process. Apoptosis, the first genetically programmed death process identified, has been extensively studied and itsExpand
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Molecular definitions of autophagy and related processes
Over the past two decades, the molecular machinery that underlies autophagic responses has been characterized with ever increasing precision in multiple model organisms. Moreover, it has become clearExpand
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Peculiarities of cell death mechanisms in neutrophils
Analyses of neutrophil death mechanisms have revealed many similarities with other cell types; however, a few important molecular features make these cells unique executors of cell death mechanisms.Expand
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Autophagy in malignant transformation and cancer progression
Autophagy plays a key role in the maintenance of cellular homeostasis. In healthy cells, such a homeostatic activity constitutes a robust barrier against malignant transformation. Accordingly, manyExpand
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Refining the definition of hypereosinophilic syndrome.
Because of advances in our understanding of the hypereosinophilic syndrome (HES) and the availability of novel therapeutic agents, the original criteria defining these disorders are becomingExpand
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Apoptotic Pathways Are Inhibited by Leptin Receptor Activation in Neutrophils1
Leptin regulates food intake as well as metabolic, endocrine, and immune functions. It exerts proliferative and antiapoptotic activities in a variety of cell types, including T cells. Leptin alsoExpand
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Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper
 Nonallergic rhinitis (NAR) can be defined as a chronic nasal inflammation which is not caused by systemic IgE‐dependent mechanisms. It is common and probably affects far more than 200 million peopleExpand
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