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A Randomized Controlled Trial of Multicomponent Exercise in Older Adults with Mild Cognitive Impairment
Background To examine the effect of multicomponent exercise program on memory function in older adults with mild cognitive impairment (MCI), and identify biomarkers associated with improvement of… Expand
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
Summary Background The MTHFR 677C→T polymorphism has been associated with raised homocysteine concentration and increased risk of stroke. A previous overview showed that the effects were greatest in… Expand
Age-related changes in intraocular pressure in a large Japanese population: a cross-sectional and longitudinal study.
OBJECTIVE To assess the influence of aging, blood pressure, and body mass index (BMI) on intraocular pressure (IOP) in a large Japanese population. DESIGN Cross-sectional and longitudinal study. … Expand
The relationship between age and intraocular pressure in a Japanese population: The influence of central corneal thickness
- H. Nomura, F. Ando, N. Niino, H. Shimokata, Y. Miyake
- Biology, Medicine
- Current eye research
- 1 January 2002
Purpose. Previous cross-sectional Japanese studies have shown that intraocular pressure (IOP) decreases with age. However, central corneal thickness (CCT) variation should also be considered when… Expand
Relationship between intraocular pressure and obesity in Japan.
- K. Mori, F. Ando, H. Nomura, Y. Sato, H. Shimokata
- International journal of epidemiology
- 1 August 2000
BACKGROUND Some cross-sectional studies have suggested that age, systolic blood pressure and obesity are positively related to intraocular pressure (IOP), but few longitudinal studies have examined… Expand
Studies in the distribution of body fat. III. Effects of cigarette smoking.
Cross-sectional associations between smoking habits, body mass index, and waist-hip ratio (WHR) were examined in 1122 men aged 19 to 102 years. Weight and body mass index were significantly lower in… Expand
Studies in the distribution of body fat: I. Effects of age, sex, and obesity.
- H. Shimokata, J. Tobin, D. C. Muller, D. Elahi, P. Coon, R. Andres
- Journal of gerontology
- 1 September 1989
The pattern of body fat distribution has been shown to be related to a large number of variables of clinical importance. A variety of indices have been devised, many of them simple enough to be… Expand
Refractive errors and factors associated with myopia in an adult Japanese population.
- Naoko Shimizu, H. Nomura, F. Ando, N. Niino, Y. Miyake, H. Shimokata
- Japanese journal of ophthalmology
PURPOSE To investigate the refractive status and factors associated with myopia by a population-based survey of Japanese adults. METHODS A total of 2168 subjects aged 40 to 79 years, randomly… Expand
Association of polymorphisms of the estrogen receptor α gene with bone mineral density of the femoral neck in elderly Japanese women
- Y. Yamada, F. Ando, N. Niino, S. Ohta, H. Shimokata
- Medicine, Biology
- Journal of Molecular Medicine
- 4 June 2002
The estrogen receptor α gene is a candidate locus for genetic influence on bone mass. The possible association between two polymorphisms in the first intron of this gene, alone or in combination, and… Expand
Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort
Objective:To investigate whether Leu72Met polymorphism of the preproghrelin gene is associated with overweight/obesity in middle-aged and older Japanese.Design:Cross-sectional analysis.Subjects:A… Expand