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Cost-Minimization of Amino Acid Usage
- H. Seligmann
- BiologyJournal of Molecular Evolution
- 1 February 2003
Empirical results support that free-living organisms minimize the usage of heavy amino acids more than intracellular organisms and preliminary results suggest that for different proteins, the evolutionary rate of amino acid replacements correlates negatively with WM in these proteins.
Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere
Tupanvirus is a unique giant virus that has an unusually long tail and contains the largest translational apparatus of the known virosphere and their genetic analysis can provide insights into virus evolution.
The ambush hypothesis: hidden stop codons prevent off-frame gene reading.
High hidden stop density seems to be an adaptation in species with slippage prone ribosomes (unstable rRNAs), and may compensate for reduced efficiency of some parts of the biosynthetic machinery.
Detecting gradients of asymmetry in site-specific substitutions in mitochondrial genomes.
The implementation of a simple hidden Markov model (HMM) of among-site rate correlations is described to provide an almost continuous profile of the asymmetry in substitution response for any particular substitution type, using a phylogeny-based Bayesian Markov chain Monte Carlo approach.
Ancestral sequence reconstruction in primate mitochondrial DNA: compositional bias and effect on functional inference.
- N. Krishnan, H. Seligmann, C. Stewart, A. D. de Koning, D. Pollock
- BiologyMolecular biology and evolution
- 1 October 2004
It is found that maximum likelihood reconstructs ancestral frequencies that are often more different from tip sequences than are parsimony reconstructions, and nucleotide bias in reconstructed sequences apparently can lead to serious bias and inaccuracies in functional predictions.
Evolution of base-substitution gradients in primate mitochondrial genomes.
- Sameer Z. Raina, J. Faith, T. Disotell, H. Seligmann, C. Stewart, D. Pollock
- BiologyGenome research
- 1 May 2005
A methodology was developed to evaluate the posterior probability densities of the response parameter space, and used likelihood ratio tests and mixture models with different numbers of classes to determine whether groups of genomes have evolved in a similar fashion.
Morphological, functional and evolutionary aspects of tail autotomy and regeneration in the 'living fossil' Sphenodon (Reptilia: Rhynchocephalia)
The variation in the location of tail injury was correlated with the continuum of variation between injured and intact (pholidotic) morphotypes, and the last two phenomena remain to be explored in Squamates.
Codon expansion and systematic transcriptional deletions produce tetra-, pentacoded mitochondrial peptides.
- H. Seligmann
- BiologyJournal of theoretical biology
- 21 December 2015
Behavioural and morphological asymmetries in hindlimbs of Hoplodactylus duvaucelii (Lacertilia: Gekkonomorpha: Gekkota: Diplodactylinae)
- H. Seligmann
- 1 June 2002
An association of behavioural and morphological directional asymmetries at the level of individual lizards is reported and it is shown that in geckos, clinging ability increases with the number of subdigital lamellae, especially after variation in body mass is accounted for.
Systematics and distribution of the Acanthodactylus pardalis group (Lacertidae) in Egypt and Israel
Results confirmed the occurrence of two allopatric species in this area: Acanthodactylus pardalis (Lichtenstein, 1823) distributed in Egypt And eastern Libya and a hitherto undescribed species endemic to the Negev (Israel).