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Functional Cloning and Characterization of a Multidrug Efflux Pump, MexHI-OpmD, from a Pseudomonas aeruginosa Mutant
ABSTRACT We isolated mutant YM644, which showed elevated resistance to norfloxacin, ethidium bromide, acriflavine, and rhodamine 6G, from Pseudomonas aeruginosa YM64, a strain that lacks four majorExpand
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Gene cloning and properties of the RND-type multidrug efflux pumps MexPQ-OpmE and MexMN-OprM from Pseudomonas aeruginosa.
We cloned two operons for putative RND-type multidrug efflux pumps from Pseudomonas aeruginosa by a PCR method. We designated the genes in one operon mexPQ(-opmE) and in another operon mexMN.Expand
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Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens
Clostridium perfringens produces potent toxins and histolytic enzymes, causing various diseases including life-threatening fulminant diseases in humans and other animals. Aiming at utilizing a phageExpand
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X-ray structure of a novel endolysin encoded by episomal phage phiSM101 of Clostridium perfringens.
Gram-positive bacteria possess a thick cell wall composed of a mesh polymer of peptidoglycans, which provides physical protection. Endolysins encoded by phages infecting bacteria can hydrolyseExpand
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Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa.
muxA-muxB-muxC-opmB (formerly PA2528-PA2527-PA2526-opmB), encoding a putative resistance nodulation cell division (RND)-type multidrug efflux pump system, was cloned from Pseudomonas aeruginosa PAO1.Expand
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Inhibitory Effects of Fruit Juices on Cytochrome P450 2C9 Activity in Vitro
There is limited information on the effect of fruits on human cytochrome P450 (CYP) 2C9 activity. The objective of this study was to determine the effect of fruit juice on CYP2C9-mediated drugExpand
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ANOMALOUS SEISMIC ACTIVITY AND EARTHQUAKE PREDICTION
The earthquake off the Izu Peninsula, on May 9, 1974 (M=6.9) was preceded by an anomalous seismic activity which started about 10 years and 4 months before, in July 1963 and can be distinguished fromExpand
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Excited-state double-proton transfer in a model DNA base pair : Resolution for stepwise and concerted mechanism controversy in the 7-azaindole dimer revealed by frequency- and time-resolved
Abstract The excited-state double-proton transfer (ESDPT) reaction in the dual hydrogen-bonded 7-azaindole dimer (7AI 2 ) in a supersonic jet expansion has been extensively studied with various laserExpand
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Excited-state intramolecular proton transfer and charge transfer in 2-(2'-hydroxyphenyl)benzimidazole crystals studied by polymorphs-selected electronic spectroscopy.
Crystal structures of polymorphs of 2-(2'-hydroxyphenyl)benzimidazole (HPBI), Forms α and β, are analyzed by X-ray crystallography. The fluorescence excitation (FE) and fluorescence spectra of theExpand
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TUNNELING IN JET-COOLED 5-METHYLTROPOLONE AND 5-METHYLTROPOLONE-OD. COUPLING BETWEEN INTERNAL ROTATION OF METHYL GROUP AND PROTON TRANSFER
The coupling of two large amplitude motions, the internal rotation of the methyl group and the intramolecular proton transfer, has been investigated for jet-cooled 5-methyltropolone,Expand
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