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A double‐blind multicentre study comparing remoxipride, two and three times daily, with haloperidol in schizophrenia
TLDR
Treatment‐emergent extrapyramidal checklist symptoms (hypokinesia, rigidity and tremor) were statistically significantly more frequent and more severe during haloperidol than during remoxipride treatment despite a statistically significantly higher concurrent use of anticholinergic drugs in the hal operidol group. Expand
Effects of topically applied antiandrogenic compounds on sebaceous glands of hamster ears and flank organs.
TLDR
The view that the DHT formation rate has no regulatory function for growth of sebaceous glands in hamsters is supported and that PM and PRO counteract the androgenic stimulus by their competitive antagonistic binding to the androgens receptor, but not by their influence on testosterone metabolism. Expand
Effect of cyproterone acetate in comparison to flutamide and megestrol acetate on the ventral prostate, seminal vesicle, and adrenal glands of adult male rats
TLDR
A critical review of all available data on the antiandrogenic, glucocorticoidlike, and possible paradoxical androgenlike activities of CPA in different animal experiments has no important bearing on the clinical effectiveness of C PA in the treatment of prostatic cancer. Expand
Experimental studies on the endocrine side effects of new aldosterone antagonists.
TLDR
The results suggest that mespirenone seems to be a suitable candidate for development as a clinically useful aldosterone antagonist. Expand
Aromatase-inhibitors of the androstenedione-type activate the 17 beta-hydroxysteroid-dehydrogenase in the rat testis tissue suspension model.
TLDR
The results imply that aromatase inhibitors may regulate the intratissular levels not only of estrogens but also of other hormonally active steroids like dihydrotestosterone and 5-androstenedione. Expand
Effect of cyproterone acetate in comparison to flutamide and megestrol acetate on the ventral prostate, seminal vesicle, and adrenal glands of adult male rats.
TLDR
A critical review of all available data on the antiandrogenic, glucocorticoidlike, and possible paradoxical androgenlike activities of CPA in different animal experiments has no important bearing on the clinical effectiveness of C PA in the treatment of prostatic cancer. Expand
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