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Inhibition of human immunodeficiency viral replication by tannins and related compounds.
Stimulation of human monocyte and polymorphonuclear cell iodination and interleukin‐1 production by epigallocatechin gallate
The data suggest that EGCg is a strong in vitro stimulant of human phagocytes, and various immunoregulators such as lipopolysaccharide (LPS), opsonized zymosan, 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) and tumor necrosis factor stimulated PMN iodination to varying degrees, their ability to stimulate monocyte iodination was much lower than that of E GCg.
Stimulation of granulocytic cell iodination by tannins and related compounds.
The results suggest that the stimulation activity of tannins and related polyphenols might depend more on their molecular weights than the number of hydroxyl groups on each benzene ring in the molecule, or the presence of sugars or hexahydroxydiphenoyl groups.
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.
Observations indicate that early inhibition of DNA synthesis, with sparing of RNA and protein synthesis, is characteristic of the differentiation-inducing antineoplastic drugs examined.
Prevention of phorbol ester receptor down modulation in human myeloblastic leukemia ML-1 cells by differentiation-stimulating serum components.
The currently described alteration of phorbol ester receptor activity by differentiation-inducing factors implies an interaction between growth and differentiation factors in receptor modulation.
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
The activity of asparagine synthetase decreased almost 50% during dexamethasone-induced mouse myeloid leukemia M1 cell differentiation. This enzyme activity also declined significantly during…
Differentiation-associated changes in human non-T, non-B leukemia cell lines after treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA).
Effect of sera of brain tumor patients on cytokine-induced human myelogenous leukemic cell differentiation.
The results suggest that the weak differentiation-stimulating effect of the serum of brain tumor patients cannot be explained simply by the modification of the binding of these cytokines to cellular receptors.
Inhibition of tumor necrosis factor-stimulated human peripheral blood polymorphonuclear cell iodination by sera from various cancer patients.
- M. Ikeda, H. Sakagami, H. Nishida, Y. Hatta, Y. Fukushima
- Medicine, BiologyAnticancer research
- 1 September 1991
Data suggest some mechanism other than modification of TNF receptor binding for expression of the inhibitory action of cancer patient serum is responsible for TNF-stimulated iodination of human peripheral blood monocytes.
The Influence of Several Endocrine Factors upon the Growth of Pigment-Epithelium of the Retina Cultivated in vitro, with Special Reference to the Influence upon the Distribution of Pigment Granules…
- H. Sakagami
Using the retina of chick embryo, tissue culture experiments were performed by single cover slip method or by roller test tubes, and the growing process of pigment epithelium is measured by planometric means.