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Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity.
- T. Kakinuma, K. Nakamura, +8 authors K. Tamaki
- The Journal of allergy and clinical immunology
- 1 March 2001
BACKGROUND Atopic dermatitis (AD) is a chronic and relapsing inflammatory skin disease characterized by the predominant infiltration of TH2-type cells in lesional skin. Thymus and… Expand
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population
Atopic dermatitis is a common inflammatory skin disease caused by interaction of genetic and environmental factors. On the basis of data from a genome-wide association study (GWAS) and a validation… Expand
Guidelines for management of atopic dermatitis
Atopic dermatitis (AD) is a chronic relapsing eczematous skin disease characterized by pruritus and inflammation and accompanied by cutaneous physiological dysfunction (dry and barrier‐disrupted… Expand
Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.
- Y. Tsunemi, H. Saeki, +14 authors K. Tamaki
- Medicine, Biology
- Journal of dermatological science
- 1 November 2002
Interleukin-12 (IL-12) is believed to play an important role in inducing Th1-type cytokine profiles. Atopic dermatitis (AD) and psoriasis vulgaris (PsV) are considered to be Th2 and Th1 type disease,… Expand
Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases.
Thymus and activation-regulated chemokine (TARC)/CCL17 is constitutively expressed in the thymus and is produced by dendritic cells (DC), endothelial cells, keratinocytes (KC) and fibroblasts. TARC… Expand
Imatinib mesylate inhibits the growth of metastatic lung lesions in a patient with dermatofibrosarcoma protuberans
- K. Mizutani, Y. Tamada, +4 authors Y. Matsumoto
- The British journal of dermatology
- 1 July 2004
derived from the neural crest, whereas Langerhans cells are derived from bone marrow. Merkel cells are considered to originate from the neural crest and to form specialized nerve endings. Thus, it is… Expand
Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016
Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. Most patients have an atopic predisposition. The definitive diagnosis of AD requires the… Expand
Efficacy and safety of open‐label ixekizumab treatment in Japanese patients with moderate‐to‐severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis
- H. Saeki, H. Nakagawa, +4 authors M. Heffernan
- Journal of the European Academy of Dermatology…
- 1 June 2015
Ixekizumab, an anti‐IL‐17A monoclonal antibody, demonstrated a high level of efficacy in moderate‐to‐severe plaque psoriasis (PP) patients.
Serum high molecular weight adiponectin levels are decreased in psoriasis patients.
Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens
Ichthyosis bullosa of Siemens (IBS) is an autosomal dominant skin disorder that resembles epidermolytic hyperkeratosis (EHK). We have indentified mutations in two families originally diagnosed with… Expand