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Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report.

TLDR
When more treatment steps are required, lower acute remission rates (especially in the third and fourth treatment steps) and higher relapse rates during the follow-up phase are to be expected.
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Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial

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Acute and Longer- Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

TLDR
The acute and longer-term treatment outcomes associated with each of four successive steps in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial are described and compared.
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The definition and meaning of treatment-resistant depression.

  • H. Sackeim
  • Psychology, Medicine
    The Journal of clinical psychiatry
  • 2001
TLDR
The Antidepressant Treatment History Form is presented as one method to formalize the evaluation of treatment adequacy and treatment resistance.
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A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities.

TLDR
Right unilateral ECT at high dosage is as effective as a robust form of BL ECT, but produces less severe and persistent cognitive effects.
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Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy.

TLDR
increasing the electrical dosage increases the efficacy of right unilateral electroconvulsive therapy, although not to the level of bilateral therapy, and unilateral treatment is associated with less severe cognitive side effects after treatment.
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Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design.

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Effects of pulse width and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy

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Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial.

TLDR
Daily left prefrontal repetitive transcranial magnetic stimulation as monotherapy produced statistically significant and clinically meaningful antidepressant therapeutic effects greater than sham.
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Report by the ACNP Task Force on Response and Remission in Major Depressive Disorder

TLDR
Recommendations suggest that symptom ratings that measure all nine criterion symptom domains to define a major depressive episode are preferred as they provide a more certain ascertainment of remission.
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