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Urine glycoprotein crystal growth inhibitors. Evidence for a molecular abnormality in calcium oxalate nephrolithiasis.
One reason that some people are prone to calcium oxalate nephrolithiasis is that they produce urine that is subnormal in its ability to inhibit the growth of calcium oxalate crystals. We haveExpand
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Role of sugars in human neutrophilic phagocytosis.
This study was designed to test a) whether carbohydrates other than glucose decreased the phagocytic capacity of neutrophils in normal human subjects, b) the duration of this effect, and c) theExpand
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Kinetics, dynamics, and bioavailability of bumetanide in healthy subjects and patients with chronic renal failure
Six patients with chronic renal failure (CRF group) and four healthy subjects (HS group) were given 5 mg oral and intravenous doses of bumetanide in a random, crossover design. The CRF group hadExpand
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Effect of probenecid on the dose-response relationship of bumetanide at steady state.
  • H. S. Lau, L. Shih, D E Smith
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1 October 1983
The present investigation was undertaken to clarify the determinants of the pharmacologic responses to bumetanide. The urinary excretion rate, plasma concentration and natriuretic and diureticExpand
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Absorption of Flurbiprofen in the Fed and Fasted States
The oral absorption of flurbiprofen, an antiinflammatory nonsteroidal compound, was compared in the fasted vs the fed state. When ingested as an aqueous solution of the sodium salt, absorptionExpand
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Determinants of bumetanide response in the dog: effect of indomethacin.
  • D E Smith, H. S. Lau
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
  • 1 November 1983
Four male unanesthetized dogs each weighing 22.0-29.0 kg received 0.250 mg/kg iv of bumetanide before (treatment I) and after (treatment II) indomethacin pretreatment. Lactated Ringer's solution wasExpand
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Determinants of bumetanide response in the dog: Effect of probenecid
  • David E. Smith, H. S. Lau
  • Chemistry, Medicine
  • Journal of Pharmacokinetics and Biopharmaceutics
  • 1 February 1983
The pharmacokinetics and pharmacodynamics of intravenous bumetanide (0.250 mg/kg), alone (treatment I) and after probenecid pretreatment (treatment II), were studied in four mongrel dogs. LactatedExpand
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Effect of food on the bioavailability of adinazolam from a sustained release formulation: Effect of meal timing and lack of dose dumping
Food effects on adinazolam absorption from sustained release (SR) adinazolam mesylate tablets were assessed in 28 healthy male volunteers. Subjects received 15 mg SR tablets. 15 mg immediate releaseExpand
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[Poisoning with organophosphate compounds].
A 50-year-old man swallowed 200 ml of an insecticide containing the organophosphates dimethoate and phenitrotion in an attempted suicide. On admission, signs of a cholinergic syndrome were observed:Expand
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EFFECT OF URIC ACID ON RIBOFLAVINE PRODUCTION BY INTESTINAL COLIFORM BACTERIA.
Lau, H. S. (University of Kentucky, Lexington), and R. F. Wiseman. Effect of uric acid on riboflavine production by intestinal coliform bacteria. J. Bacteriol. 87:337-340. 1964.-Cultures ofExpand
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