H. S. Kim
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Inheritance of partial resistance to Sclerotinia stem rot in soybean.
Little is known about the inheritance of partial resistance in soybean [Glycine max (L.) Merr.] to sclerotinia stem rot, caused by the fungal pathogen Sclerotinia sclerotiorum (Lib.) de Bary. This… Expand
Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
The current gene transfer technology for single chain (scFv)-based chimeric immune receptor (CIR) has relied on retrovirus and lentivirus vectors which require a long time to obtain sufficient number… Expand
Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway.
The consumption of caffeine from some common beverages has been associated with low bone mass by inducing urinary calcium loss and deceasing bone mineral density. However, the effect of caffeine on… Expand
Comparative study of chitosan/fibroin–hydroxyapatite and collagen membranes for guided bone regeneration in rat calvarial defects: micro-computed tomography analysis
- J. M. Song, S. H. Shin, +4 authors H. S. Kim
- Biology, Medicine
- International Journal of Oral Science
- 11 April 2014
This study aimed to utilize micro-computed tomography (micro-CT) analysis to compare new bone formation in rat calvarial defects using chitosan/fibroin–hydroxyapatite (CFB–HAP) or collagen (Bio-Gide)… Expand
Host lymphodepletion enhances the therapeutic activity of an oncolytic vaccinia virus expressing 4-1BB ligand.
Oncolytic viral vectors have shown promise as antitumor therapeutic agents but their effectiveness is complicated by induction of antiviral antibody responses and rapid host clearance of recombinant… Expand
In vitro and in vivo gene-transferring characteristics of novel cationic lipids, DMKD (O,O'-dimyristyl-N-lysyl aspartate) and DMKE (O,O'-dimyristyl-N-lysyl glutamate).
Abstract We chemically synthesized two different cationic lipids consisting of a core of lysine, two C-14 hydrocarbon chains, and either aspartatic acid or glutamic acid. The lipids were assigned the… Expand
Hepatic control elements promote long‐term expression of human coagulation factor IX gene in hydrodynamically transfected mice
- H. S. Kim, J. C. Kim, Y. Lee, J. Kim, Y. S. Park
- Biology, Medicine
- The journal of gene medicine
- 1 July 2011
Long‐term expression of the delivered target gene is critical for successful gene therapy. Recently, hepatic control region I (HCR I) originating from the apolipoprotein (apo)C‐I pseudogene was shown… Expand
Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment.
- S. Kim-schulze, H. S. Kim, Q. Fan, D. Kim, H. L. Kaufman
- Medicine, Biology
- Molecular therapy : the journal of the American…
- 1 February 2009
The eradication of tumors by the immune system depends on the generation of antigen-specific T cells which can migrate to sites of tumor growth and maintain their effector functions despite local… Expand
Inhibitory effect of the salmosin gene transferred by cationic liposomes on the progression of B16BL6 tumors.
Salmosin is a novel disintegrin containing the Arg-Gly-Asp sequence that significantly inhibits platelet aggregation, basic fibroblast growth factor-induced endothelial cell proliferation, and tumor… Expand
Gene-transferring efficiencies of novel diamino cationic lipids with varied hydrocarbon chains.
Utilizing three biocompatible components, a series of novel cationic lipids has been chemically synthesized and tested for their gene-transferring capabilities in 293 transformed kidney cells and… Expand