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Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward
This article reviews progress in chemopreventive drug development, especially data and concepts that are new since the 2002 AACR report on treatment and prevention of intraepithelial neoplasia.Expand
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Vulvar intraepithelial neoplasia (VIN 2/3): comparing clinical outcomes and evaluating risk factors for recurrence.
OBJECTIVE To evaluate demographic and clinical characteristics associated with the development of vulvar intraepithelial neoplasia (VIN 2/3), and factors associated with recurrence. METHODS AExpand
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Diffuse reflectance patterns in cervical spectroscopy.
OBJECTIVES Our laboratory seeks to develop minimally invasive cost-effective methods to improve screening and detection of curable precursors to cervical cancer. Previously, we have presented pilotExpand
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Vaginal Intraepithelial Neoplasia (VaIN 2/3): Comparing Clinical Outcomes of Treatment With Intravaginal Estrogen
Objective To determine the outcomes of women treated for vaginal intraepithelial neoplasia grade 2/3 (VaIN 2/3) with intravaginal estrogen. Material and Methods A retrospective chart review wasExpand
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Risk of residual disease and invasive carcinoma in women treated for adenocarcinoma in situ of the cervix.
OBJECTIVE Cervical adenocarcinoma in situ (AIS) is increasing in incidence among reproductive-age women. Cervical conization is an alternative to hysterectomy that allows future fertility, howeverExpand
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Accuracy of optical spectroscopy for the detection of cervical intraepithelial neoplasia: Testing a device as an adjunct to colposcopy
Testing emerging technologies involves the evaluation of biologic plausibility, technical efficacy, clinical effectiveness, patient satisfaction, and cost‐effectiveness. The objective of this studyExpand
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Verruciform xanthoma in an adolescent: a case report.
BACKGROUND Verruciform xanthoma is a benign mucocutaneous, verrucous, papillary lesion characterized by large foam cells in the parakeratotic layer, lipid-laden macrophages (xanthoma cells),Expand
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Epidemiologic differentiation of diagnostic and screening populations for the assessment of cervical dysplasia using optical technologies.
BACKGROUND We report here the logistic modeling of the epidemiologic differences between a diagnostic population and a screening population recruited for the study of optical technologies forExpand
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Abnormal Uterine Bleeding as the Presenting Symptom of Hematologic Cancer
OBJECTIVE: To estimate the percentage of women with a hematologic cancer who present with abnormal uterine bleeding (AUB). METHODS: We performed a retrospective analysis of the records of women withExpand
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