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Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19
There was no association between any single medication class and an increased likelihood of a positive test for Covid-19 or in the risk of severe Covd-19 among patients who tested positive in association with five common classes of antihypertensive medications. Expand
ESC working group position paper on myocardial infarction with non-obstructive coronary arteries.
The management of acute myocardial infarction (AMI)1 has evolved over the past century and particularly in the past 50 years. Important milestones include the development of the electrocardiogram,Expand
Cardiogenic Shock: Current Concepts and Improving Outcomes
The case will be made for viewing CS as a serious disorder with a high early death rate, but one that is treatable and that, if approached aggressively, can result in full recovery. Expand
ST-Segment Elevation in Patients with Covid-19 — A Case Series
Eight patients with Covid-19 presented with ST-segment elevation on ECG or had it develop during hospitalization and eight patients received a diagnosis of acute my... Expand
Initial Invasive or Conservative Strategy for Stable Coronary Disease.
Evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years is not found. Expand
Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association
This statement provides a formal and updated definition for the broadly labelled term MINOCA (incorporating the definition of acute myocardial infarction from the newly released “Fourth Universal Definition of Myocardial Infarction”) and provides a clinically useful framework and algorithms for the diagnostic evaluation and management of patients with myocardia in the absence of obstructive coronary artery disease. Expand
Coronary intervention for persistent occlusion after myocardial infarction.
PCI did not reduce the occurrence of death, reinFarction, or heart failure, and there was a trend toward excess reinfarction during 4 years of follow-up in stable patients with occlusion of the infarct-related artery 3 to 28 days after myocardial infarction. Expand
Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial.
Tilarginine, 1-mg/kg bolus and 5-hour infusion, did not reduce mortality rates in patients with refractory cardiogenic shock complicating acute myocardial infarction despite establishment of an open infarct artery. Expand
Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series
In this series of seven COVID-19 autopsies, thrombosis was a prominent feature in multiple organs, in some cases despite full anticoagulation and regardless of timing of the disease course, suggesting that thROMbosis plays a role very early in the disease process. Expand
Mechanisms of Myocardial Infarction in Women Without Angiographically Obstructive Coronary Artery Disease
Plaque rupture and ulceration are common in women with myocardial infarction without angiographically demonstrable obstructive coronary artery disease, and LGE is common in this cohort of women, with an ischemic pattern of injury most evident. Expand