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REVIEW: Intrahepatic cholestasis. A puzzling disorder of pregnancy
- H. Reyes
- Journal of gastroenterology and hepatology
- 1 March 1997
Intrahepatic cholestasis of pregnancy is characterized by skin pruritus and a biochemical cholestasis of mild to moderate severity appearing during pregnancy (mainly in the third trimester) and… Expand
Ursodeoxycholic acid in the treatment of cholestasis of pregnancy: a randomized, double-blind study controlled with placebo.
BACKGROUND/AIMS Intense pruritus and the risk of stillbirths and premature deliveries justify the search for an effective pharmacologic treatment of intrahepatic cholestasis of pregnancy. This study… Expand
The Enigma of Intrahepatic Cholestasis of Pregnancy: Lessons from Chile
- H. Reyes
- 21 September 2007
Acute fatty liver of pregnancy: a clinical study of 12 episodes in 11 patients.
Twelve episodes of acute fatty liver of pregnancy (AFLP) were diagnosed in 11 patients during the past 18 years in a general hospital in Santiago, Chile, with a prevalence of 1 per 15,900 deliveries.… Expand
Intrahepatic cholestasis of pregnancy in twin pregnancies.
To clarify whether the increase in estrogen levels occurring during twin pregnancies (TP) is associated with a greater risk of developing intrahepatic cholestasis of pregnancy (ICP), we followed up… Expand
Bile acids and progesterone metabolites intrahepatic cholestasis of pregnancy
The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) can be related to abnormalities in the metabolism and disposition of sex hormones and/or bile acids, determined by a genetic… Expand
Selenium, zinc and copper plasma levels in intrahepatic cholestasis of pregnancy, in normal pregnancies and in healthy individuals, in Chile.
BACKGROUND/AIMS Low blood Se levels have been previously shown in normal pregnancies (third trimester) and significantly lower levels in patients with intrahepatic cholestasis of pregnancy (ICP), in… Expand
Intrahepatic cholestasis of pregnancy: a past and present riddle.
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific disorders that occurs mainly in the third trimester of pregnancy and is characterized by pruritus and elevated bile acid levels.… Expand
Effects of ursodeoxycholic acid in patients with intrahepatic cholestasis of pregnancy
The efficacy and safety of ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy was investigated in an open pilot study. Five patients received 1 gm/day of ursodeoxycholic… Expand
Intrahepatic cholestasis of pregnancy: an estrogen-related disease.
In the recent years new avenues have been opened in the treatment of ICP, a complex disorder that seems to represent a maladaptation of some young and otherwise healthy women, to estrogens or other… Expand