• Publications
  • Influence
Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.
TLDR
Measurement of the combined local synthesis of antibodies against measles, rubella, and/or varicella zoster could represent a significant advance if it offers higher specificity (not sensitivity) for identifying chronic rather than acute inflammation.
Dynamics of brain-derived proteins in cerebrospinal fluid.
  • H. Reiber
  • Biology, Medicine
    Clinica chimica acta; international journal of…
  • 20 August 2001
Cerebrospinal fluid - physiology, analysis and interpretation of protein patterns for diagnosis of neurological diseases
  • H. Reiber
  • Medicine, Biology
    Multiple sclerosis
  • 1 June 1998
The state of the art in routine CSF analysis is reviewed with particular reference to multiple sclerosis regarding: (1) The physiology and pathophysiology of blood-CSF barrier function and
The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis
TLDR
The difference between brain ratio and blood ratio is discussed to be indicative for the anti-MRZ antibody forming B-lymphocyte subset in blood migrating into brain at earlier time of pathophysiological start of disease.
Proteins in cerebrospinal fluid and blood: barriers, CSF flow rate and source-related dynamics.
  • H. Reiber
  • Biology
    Restorative neurology and neuroscience
  • 2003
TLDR
The review of the anatomical, physiological and biophysical knowledge points to the new interpretations: the changing albumin quotient is an indicator of changing CSF flow rate and not for a morphological "leakage" of the blood-brain barrier.
Quantification of virus-specific antibodies in cerebrospinal fluid and serum: sensitive and specific detection of antibody synthesis in brain.
TLDR
The method has applied successfully to antibodies to measles, rubella, herpes simplex, varicella-zoster, human immunodeficiency virus, and cytomegalovirus, and to anti-Toxoplasma or -Borrelia antibodies.
Paediatric and adult multiple sclerosis: age-related differences and time course of the neuroimmunological response in cerebrospinal fluid
TLDR
Paediatric MS already at first clinical manifestation shows the complete, neuroimmunological data pattern in CSF, i.e. inflammatory signs are not gradually evolving, and CSF analysis may help to discriminate between acute and mono-symptomatic chronic inflammatory disease already at earliest clinical manifestation.
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