Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs
Cerebrospinal fluid (CSF) analysis is a basic tool for diagnosis of neurological diseases. Knowledge regarding blood-CSF barrier function (molecular flux/CSF flow theory) and neuroimmunology is… Expand
Flow rate of cerebrospinal fluid (CSF) — A concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases
- H. Reiber
- Medicine
- Journal of the Neurological Sciences
- 1 April 1994
Many neurological diseases are accompanied by increased protein concentrations in the cerebrospinal fluid (CSF), described as a blood-CSF barrier dysfunction. The earlier interpretation as a… Expand
Dynamics of brain-derived proteins in cerebrospinal fluid.
- H. Reiber
- Chemistry, Medicine
- Clinica chimica acta; international journal of…
- 20 August 2001
BACKGROUND
The recent theory of blood-cerebrospinal fluid (CSF) barrier function and dysfunction connects molecular flux and CSF flow rate. A reduced CSF flow rate is sufficient to account for the… Expand
The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis
- H. Reiber, S. Ungefehr, C. Jacobi
- Medicine
- Multiple sclerosis
- 1 June 1998
We report an extended set of neuroimmunological data detected in cerebrospinal fluid (CSF) from n=267 patients with definite multiple sclerosis (MS). Known frequencies of oligoclonal IgG (98%),… Expand
Cerebrospinal fluid - physiology, analysis and interpretation of protein patterns for diagnosis of neurological diseases
- H. Reiber
- Medicine
- Multiple sclerosis
- 1 June 1998
The state of the art in routine CSF analysis is reviewed with particular reference to multiple sclerosis regarding: (1) The physiology and pathophysiology of blood-CSF barrier function and… Expand
Quantification of virus-specific antibodies in cerebrospinal fluid and serum: sensitive and specific detection of antibody synthesis in brain.
Specific antibody synthesis in brain could be detected with maximal sensitivity by combining an advanced enzyme immunoassay with a sophisticated evaluation method that involves calculating the ratio… Expand
Proteins in cerebrospinal fluid and blood: barriers, CSF flow rate and source-related dynamics.
- H. Reiber
- Biology, Medicine
- Restorative neurology and neuroscience
- 2003
Cerebrospinal fluid (CSF) routine analysis for diagnosis of neurological diseases is based on the concepts for discrimination of blood-derived and brain-derived immunoglobulin fractions in CSF. The… Expand
Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system.
- H. Reiber, K. Felgenhauer
- Chemistry, Medicine
- Clinica chimica acta; international journal of…
- 30 March 1987
The cerebrospinal fluid (CSF)/serum concentration quotients of albumin and the immunoglobulins G, A and M have been determined for 396 patients with a normal blood CSF barrier function or a pure… Expand
Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction.
- K. Bechter, H. Reiber, S. Herzog, D. Fuchs, H. Tumani, H. Maxeiner
- Medicine, Psychology
- Journal of psychiatric research
- 1 April 2010
Immune and inflammatory mechanisms are detected in a subgroup of treatment resistant hospitalized affective and schizophrenic spectrum disorder patients. We analysed albumin, IgG, IgA, IgM,… Expand
Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis
- H. Tumani, Georg Nolker, H. Reiber
- Medicine
- Neurology
- 1 September 1995
We describe the specificity and sensitivity of measuring a combination of basic CSF variables and Borrelia burgdorferi (Bb)-specific IgG and IgM antibody index (AI) values for the diagnosis of early… Expand