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Nanoscale Organization of Hedgehog Is Essential for Long-Range Signaling
Hedgehog (Hh) plays crucial roles in tissue-patterning and activates signaling in Patched (Ptc)-expressing cells. Paracrine signaling requires release and transport over many cell diameters away by a… Expand
Evolution of the nasuta-albomicans complex of Drosophila
The chromosomes of two Drosophila races: Drosophila nasuta nasuta and Drosophila nasuta albomicana V. Introgression and the evolution of new karyotypes
Reciprocal crosses were made between an Indian strain of D. n. nasuta (2n=8) and the Thailand strain of D. n. albomicana (2n=6). Hybrids were fertile. They were inbred for over four years. Later, the… Expand
Administration of ipilimumab to a liver transplant recipient with unresectable metastatic melanoma.
The CTLA-4 immune checkpoint inhibitor ipilimumab improves overall survival in metastatic melanoma. Its use in organ transplant recipients has not been studied and has been reported once in the… Expand
Molecular phylogeny of the nasuta subgroup of Drosophila based on 12S rRNA, 16S rRNA and CoI mitochondrial genes, RAPD and ISSR polymorphisms.
The nasuta subgroup is a cluster of morphologically almost similar forms with a wide range of geographic distribution. During the last three decades nature of inter-relationship among the members has… Expand
Incipient sexual isolation in thenasuta-albomicans complex ofDrosophila: mating preference in male-, female- and multiple-choice mating experiments
Interracial divergence is an important facet of speciation. Thenasuta-albomicans complex ofDrosophila with sixteen morphologically identical, karyotypically different but cross-fertile races is an… Expand
Incipient sexual isolation in thenasuta-albomicans complex ofDrosophila: No-choice experiments
Drosophila nasuta nasuta andDrosophila nasuta albomicans are cross-fertile races ofDrosophila. Hybridization between these races in the laboratory has given rise to new races (Cytoraces), among which… Expand
Isozymes and genetic divergence in the nasuta-albomicans complex of Drosophila
The nasuta-albomicans complex is a hybrid-zoned artificially created in the environs of the laboratory 1 . The members of this complex include D. nasuta, D. albomicans and a number of Cytoraces. The… Expand
Chromosomal polymorphism in Drosophila nasuta. III. Inverted gene arrangements in South Indian populations.
Inversion polymorphism, including a total of 33 inverted gene orders, was studied in South Indian populations of D. nasuta nasuta. Of these, the X chromosome has one, chromosome 2 has 10, and… Expand
The chromosomes of two Drosophila races: D. nasuta nasuta and D. nasuta albomicana
Interracial hybridization between Drosophila nasuta nasuta (2n=8) and D. n. albomicana (2n=6) has resulted in the evolution of two new karyotypic strains, called “Cytoraces” I and II. Males and… Expand