Hypotrophic type I muscle fibres with central nuclei, and central myofibrillar lysis preferentially involving type II fibres.
Two familial cases of a particular form of congenital myopathy are reported. The peculiar morphological features of the muscle included hypotrophy of type I fibres with central nuclei, and central myo
Myotubular (centronuclear) (neuro-)myopathy. I. Clinical, genetical and morphological studies.
- H. Radu, I. Killyen, V. Ionescu, A. Radu
- Medicine, BiologyEuropean Neurology
- 1977
Five new cases of myotubular (centronuclear) (neuro-)myopathy are presented, and certain morphological changes suggest denervation involving the fibres in an early stage of myogenesis.
Carrier detection in X-linked Duchenne type muscular dystrophy. A pluridimensional investigation.
- H. Radu, S. Migea, Z. Török, L. Bordeianu, A. Radu
- PsychologyJournal of Neurological Sciences
- 1 March 1968
Nemaline (neuro) myopathy. Rod-like bodies and type I fibre atrophy in a case of congenital hypotonia with denervation.
- H. Radu, V. Ionescu
- MedicineJournal of Neurological Sciences
- 1 September 1972
Myotubular (Centronuclear) (Neuro-)Myopathy
- H. Radu, I. Killyen, V. Ionescu, A. Radu
- Medicine, Biology
- 1977
Five new cases of myotubular (centronuclear) (neuro-)myopathy are presented. Myometric studies revealed type I fibre atrophy and mispositioned nuclei, at various stages between the myotubular structur
Calcium uptake and bioelectrical activity of denervated and myotonic muscle
- H. Radu, I. Gödri, E. Albu, A. Radu, R. Robu
- Medicine, BiologyJournal of Neurology Neurosurgery & Psychiatry
- 1 June 1970
The findings showed a significant increase of calcium uptake in denervated muscle, which exhibited spontaneous bioelectrical activity (fibrillations) in Steinert's disease but not to myotonia congenita, and the implications ofcium uptake disturbances in muscle electrogenesis are discussed.
[Kugelberg-Welander neurogenic pseudomyopathy].
- H. Radu, A. Seceleanu, C. Migea, Z. Török, L. Bordeianu, S. Seceleanu
- MedicineActa neurologica et psychiatrica Belgica
- 1 May 1966
A new metabolic disorder: myopathy with glycosamino(sialo)glycans accumulation.
- H. Radu, V. Ionescu, M. Georgescu, A. Radu
- BiologyEuropean Neurology
- 1974
A particular metabolic disorder consisting in the storage of a PAS-positive material in muscle is described. The storage material appears to be a glycosamino(sialo)glycan. The storage is located on th
Defect of Coenzyme-A Activity in Progressive Muscular Dystrophy
- H. Radu, A. Kapusi, K. Stenzel
- MedicineNature
- 3 August 1968
The increase of pyruvicaemia 1–4 simultaneous with the decrease of citric acid 3,4, and the normality of lactate, α-cetoglutarate and oxalacetate serum values3,4 are interesting: only the decrease in the concentration ofcitric acid would be exclusively specific to progressive muscular dystrophy.
Identification of Duchenne muscular dystrophy carriers. Electron microscopical investigation of skeletal muscle.
- V. Ionescu, H. Radu, P. Nicolescu
- MedicineArchives of pathology
- 1 August 1975
The fine structural lesions were sufficient to vertify the diagnosis of a subclinical dystrophy, and the findings were in agreement with other investigators, however, original intranuclear filamentous formations were noted in one case.
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