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Conformation and aggregation of melittin: dependence on pH and concentration.
Melittin, a 26-residue peptide from bee venom, is transformed from a largely random to a largely alpha-helical conformation at elevated pH. At 3 x 10(-5) M melittin, circular dichroism spectra show aExpand
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The mechanism of gelation of gelatin. The influence of pH, concentration, time and dilute electrolyte on the gelation of gelatin and modified gelatins.
Abstract The effects of concentration, pH, time and dilute electrolyte on the melting points of gels of gelatin and chemically modified gelatins have been investigated. At 1–5% concentration theExpand
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Chemical modification and cross-linking of proteins by impurities in glycerol.
Abstract Impurities in glycerol are shown to cross-link bovine pancreatic ribonuclease and collagen and to eliminate the Soret band of the spectrum of myoglobin. Ethylene glycol behaves similarly.Expand
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The functional groups in the gelation of gelatin.
Abstract The participation of the side-chain dissociable and polar groups of gelatin in the gelation process has been investigated by studying the gelation of gelatins chemically modified in one ofExpand
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Interactions of protein-denaturing salts with model amides.
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Spectral studies of interactions of detergents with tryptophyl compounds.
The interactions of sodium dodecylsulfate and hexadecyltrimethylammonium chloride with typtophyl model compounds were investigated by fluorescence, classical difference spectra and thermalExpand
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Thermal perturbation difference spectra and D2O vs H2O isothermal difference spectra of protein-model aromatic chromophores.
Abstract The thermal perturbation difference spectra of phenolic and indolic chromophores in water resemble the isothermal D 2 O and H 2 O spectra of these chromophores. For phenols approximatelyExpand
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Titration of tyrosyl compounds in cationic, anionic and nonionic detergents.
Spectrosphotometric titrations of the tyrosyls of ribonuclease, reduced ribonuclease and positively charged model compounds in sodium dodecyl sulfate result in changes in pK, sharpness of titrationExpand
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Spontaneous cross-linking of collagen: evidence for metal-catalyzed and oxidative reactions.
Abstract Incubation of aqueous collagen gels at about 37° is known to cause insolubilization. The clot is slowly soluble at 80–90°, but insoluble in strong denaturants; the collagen is probablyExpand
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Cross-linking of collagen and gelatin during acetylation.
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