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A duplicated motif controls assembly of zona pellucida domain proteins.
Many secreted eukaryotic glycoproteins that play fundamental roles in development, hearing, immunity, and cancer polymerize into filaments and extracellular matrices through zona pellucida (ZP)Expand
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The ZP domain is a conserved module for polymerization of extracellular proteins
Many eukaryotic extracellular proteins share a sequence of unknown function, called the zona pellucida (ZP) domain. Among these proteins are the mammalian sperm receptors ZP2 and ZP3, non-mammalianExpand
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Secretion and assembly of zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs for mZP2 and mZP3.
The zona pellucida (ZP) is a highly organized extracellular coat that surrounds all mammalian eggs. The mouse egg ZP is composed of three glycoproteins, called mZP1-3, that are synthesized, secreted,Expand
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Structure and function of the mammalian egg zona pellucida.
The zona pellucida is a thick extracellular coat that surrounds all mammalian eggs and preimplantation embryos. The zona pellucida supports communication between oocytes and follicle cells duringExpand
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Mouse zona pellucida glycoproteins mZP2 and mZP3 undergo carboxy-terminal proteolytic processing in growing oocytes.
The extracellular coat, or zona pellucida, of the mouse egg consists of three glycoproteins, called mZP1-3. The glycoproteins are synthesized and secreted concomitantly by growing oocytes duringExpand
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Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration
The factors controlling the transfection efficiency of cationic lipid carrier systems following intravenous administration are poorly understood. UsingExpand
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Recent aspects of mammalian fertilization research
Mammalian fertilization has been the subject of intensified research in recent times. Application of recombinant DNA, transgenic and gene targeting technology, in particular, to issues in mammalianExpand
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Egg-sperm interactions at fertilization in mammals.
Mammalian eggs are surrounded by a zona pellucida (ZP) that regulates egg-sperm teractions during fertilization. The ZP consists of long filaments composed of two glycoproteins, ZP2 and ZP3, that areExpand
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Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis.
  • H. Qi, P. Juo, +5 authors M. Chou
  • Medicine, Biology
  • Cell growth & differentiation : the molecular…
  • 1 December 2001
Rho family GTPases Rac and Cdc42 are pivotal regulators of apoptosis in multiple cell types. However, little is known about the mechanism by which these GTPases are regulated in response to apoptoticExpand
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The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4
The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4
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