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Pharmacokinetics and bioavailability of doxycycline in humans.
The bioavailability of a new tablet of 6-deoxy-5-hydroxytetracycline (doxycycline, Doxycline Plantier) was estimated relatively to an oral solution and a commercially available capsule. Each form was
Pharmacokinetic study of doxycycline polyphosphate (PPD), Hydrochloride (CHD) and base (DB)
TLDR
F Fluorimetric analysis of some of the samples confirmed the values obtained, with the exception of a few parameters such as Vd and clearance, which were lower.
Pharmacokinetics of doxycycline polyphosphate after oral multiple dosing in humans
TLDR
Nine healthy volunteers received oral multiple doses of doxycycline polyphosphate for 6 days to determine the best protocol for producing effective serum antibiotic levels during a complete period of treatment with the aid of a mathematical simulation programme.
Pharmacokinetic study of doxycycline polyphosphate after simultaneous ingestion of milk
SummaryPharmacokinetic parameters of doxycycline polyphosphate were studied in healthy volunteers after oral administration of a single 200 mg dose of this antibiotic with a breakfast containing or
Alpha 1- and alpha 2-adrenoceptor selectivity of moxisylyte (thymoxamine) and its metabolites in the pithed rat.
TLDR
Results indicate that the three drugs are preferential alpha 1-adrenoceptor antagonists in vivo, much more effective against (-)phenylephrine than B-HT 933.
Pharmacokinetics of arginine and aspartic acid administered simultaneously in the rat — III: Changes in the levels of amino acids in the plasma, liver and brain after simultaneous administration of
TLDR
The increase of GABA in the brain may be due to the simultaneous administration of arginine and aspartic acid which could induce the formation of ornithine and alpha-ketoglutaric acid respectively, two metabolites known to increase cerebral GABA.
New triterpenoid saponin derivative of caulophyllogenine and therapeutic applications
RESPECT THE INVENTION NEW triterpenoid saponin DERIVED FROM THE CAULOPHYLLOGENINE, METHOD OF EXTRACTION FROM VARIETY AND THERAPEUTIC USE Chrysantellum. SAPONIN THIS IS CHARACTERIZED AS BEING THE
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