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Patterns of T lymphocyte changes with human immunodeficiency virus infection: from seroconversion to the development of AIDS.
TLDR
Among AIDS-free prevalent seropositives, CD4 levels fell steadily over 36 months of observation, while CD8 lymphocyte counts rose dramatically at seroconversion, and among men who developed AIDS, CD8 cell levels rose slowly. Expand
IgA deficiency.
Anaphylactoid transfusion reactions associated with anti-IgA.
Abstract Six patients whose serum contains antiIgA antibodies had have serious reactions after administration of blood, plasma, or gamma-globulins, presumably due to incompatible IgA globulins. TheExpand
The natural history of transfusion-associated infection with human immunodeficiency virus. Factors influencing the rate of progression to disease.
TLDR
It is concluded that most recipients of HIV-infected blood become seropositive, that AIDS develops in about half these recipients within seven years, and that the risk may be higher whenAIDS develops in the blood donor soon after donation. Expand
Hemostatic defects in dysproteinemias.
TLDR
The mechanism of defective hemostasis is uncertain, and a bewildering inconsistency of abnormal findings, some of which appear to correlate with bleeding while others do not, is described. Expand
ACQUIRED IMMUNODEFICIENCY IN AN INFANT: POSSIBLE TRANSMISSION BY MEANS OF BLOOD PRODUCTS
TLDR
The clinical and laboratory findings in a patient suggest that he acquired a transmissible infectious agent from a blood transfusion, resulting in acquired immunodeficiency, and that this agent was not cytomegalovirus, Epstein-Barr virus, or hepatitis B virus. Expand
Evaluation of screened blood donations for human immunodeficiency virus type 1 infection by culture and DNA amplification of pooled cells.
TLDR
Silent HIV-1 infections are exceedingly rare among screened blood donors, so the current risk of HIV- 1 transmission from blood transfusions, even in high-prevalence metropolitan areas, is extremely low. Expand
Nonhemolytic Febrile Transfusion Reactions
TLDR
It is concluded thatwhite cell antibodies were the primary cause of nonhemolytic febrile transfusion reactions in this series, and that the detection of white cell antibodies and preparation of leukocyte‐poor blood continue to be procedures of practical importance in modern transfusion therapy. Expand
Possible transfusion-associated acquired immune deficiency syndrome (AIDS) - California.
TLDR
The case of a 20-month old infant from San Francisco who developed unexplained cellular immuodeficiency and opportunistic infection following multiple blood transfusions including a transfusion of platelets from a donor subsequently found to have acquired immunodeficient syndrome (AIDS) adds support to the hypothesis that AIDS is caused by an infectious agent transmitted sexually or through exposure to blood or blood products. Expand
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