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Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C
TLDR
A new model for gene regulation is proposed in which nuclear FGFR1 acts as a mediator of CRE transactivation by AII, cell depolarization, and PKC. Expand
The roles of lncRNA in hepatic fibrosis
TLDR
In this study, the activation of hepatic stellate cells (HSCs) is generally considered to be a pivotal step in hepatic fibrosis, and some lncRNAs regulates diverse cellular processes. Expand
Reactive oxygen species‐mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin‐induced apoptosis in human nasopharyngeal carcinoma CNE cells
TLDR
The findings strongly suggest that polydatin might be a promising anti‐tumor drug and the data provide the molecular theoretical basis for clinical application of polydATr, as well as provoking the generation of reactive oxygen species in CNE cells. Expand
An Important Spreading Event of the Neo-Tethys Ocean during the Late Jurassic and Early Cretaceous: Evidence from Zircon U-Pb SHRIMP Dating on Diabase in Nagarzê, Southern Tibet
Abstract  Widely distributed in Gyangze-Chigu area, southern Tibet, NW- and nearly E-W-trending diabase(gabbro)-gabbro diorite dykes are regarded as the product of the large-scale spreading of theExpand
Reactive oxygen species-mediated mitochondrial dysfunction is involved in apoptosis in human nasopharyngeal carcinoma CNE cells induced by Selaginella doederleinii extract.
TLDR
These results, offering solid evidence of the induction of mitochondria-related apoptosis in tumor cells, provide the molecular theoretical basis of clinical application of Selaginella doederleinii for the treatment of human nasopharyngeal carcinoma. Expand
Identification of a binding site on human FGF-2 for fibrinogen.
Endothelial cell adhesive interactions are mediated by both fibrinogen and fibrin, and growth is stimulated by fibroblast growth factor 2 (FGF-2). We have shown previously that FGF-2 bindsExpand
Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.
TLDR
It is demonstrated that galectin-3 plays a critical role in hensin ECM assembly by oligomerizing secreted monomeric hens in the ECM of microdissected tubules. Expand
SDF1 induction by acidosis from principal cells regulates intercalated cell subtype distribution.
TLDR
It is found by growth factor quantitative PCR array that acidosis increases expression of mRNA encoding SDF1 (or CXCL12) in kidney cortex and isolated CCDs from mouse and rabbit kidney cortex, indicating that principal cells respond to acid by producing Sdf1, which then acts on adjacent ICs. Expand
Dynamic monitoring of monocyte HLA-DR expression for the diagnosis, prognosis, and prediction of sepsis.
TLDR
An overview of the association between sepsis and HLA-DR expression in terms of the predictive value of the latter in sepsi is provided. Expand
High frame rate 2D and 3D imaging with a curved or cylindrical array
  • H. Peng, J. Lu
  • Physics
  • IEEE Ultrasonics Symposium, . Proceedings.
  • 8 October 2002
Recently, a high frame rate (HFR) imaging method based on limited diffraction beam (LDB) theory has been developed. In this method, a two-dimensional (2D) or three-dimensional (3D) image isExpand
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