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Human immunodeficiency virus downregulates podocyte apoE expression.
Apolipoprotein E (apoE) has been demonstrated to play an important role in providing protection against mesangial cell injury. In the present study, we evaluated the role of apoE and its associatedExpand
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Aldosterone promotes proximal tubular cell apoptosis: role of oxidative stress.
Aldosterone has attracted significant consideration for its role in the progression of renal injury. Since apoptotic cell loss contributes to the deterioration of renal function, we examined theExpand
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Aldosterone induces mesangial cell apoptosis both in vivo and in vitro.
Both clinical and experimental reports indicate that aldosterone contributes to the progression of renal failure independent of its hemodynamic effects. In the present study, we evaluated effect ofExpand
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Nef interaction with actin compromises human podocyte actin cytoskeletal integrity.
The HIV-1 accessory protein Nef is considered to play an important role in the development of a podocyte phenotype in HIV-1 associated nephropathy. We hypothesized that Nef may be altering theExpand
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Dialysis Membrane-Induced Oxidative Stress: Role of Heme Oxygenase-1
Dialysis membranes have been reported to induce monocyte apoptosis. We studied the role of oxidative stress in the induction of dialysis membrane-induced monocyte apoptosis. Superoxide dismutase, aExpand
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Ranolazine, Tacrolimus, and Diltiazem Might be a Hazardous Combination in a Transplant Patient
We report a case of a renal transplant patient who was maintained on tacrolimus and diltiazem therapy and developed tacrolimus toxicity leading to reversible acute kidney injury when started onExpand
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Pathological polydipsia from a brain lesion
An important diagnostic consideration in the cases of hyponatraemia is psychogenic polydipsia, especially in a predisposed individual. Urine osmolality may help in differentiating psychogenicExpand