• Publications
  • Influence
Characterization of a monoclonal antibody which detects luteinizing hormone from diverse mammalian species.
TLDR
A monoclonal antibody for LH has been produced which can be used to develop sensitive and specific RIAs in many different mammalian species and validated the use of 518B7 in detecting LH in serum. Expand
Testosterone administration to mares during estrus: duration of estrus and diestrus and concentrations of LH and FSH in plasma.
TLDR
The magnitude and timing of the LH peaks were unaffected by treatment, as was the day on which the first elevated progesterone concentration occurred, consistent with a model of F SH secretion in which ovarian androgens cause an accumulation of FSH in the pituitary during estrus in preparation for the surges that occur in FSH secretion during diestrus. Expand
Preparation of ovine interstitial cell-stimulating hormone in high yield.
TLDR
The preparation obtained by this procedure has been characterized with respect to biological activity, molecular weight, amino acid composition, and carbohydrate content and shows it to be identical with previously described preparations of purified ICSH. Expand
Biological and binding activities of equine pituitary gonadotrophins and pregnant mare serum gonadotrophin.
TLDR
Comparing PMSG with pituitary gonadotrophins from homologous species shows that the apparent dual activity of PMSG may not be a unique feature of this pregnancy hormone since equine LH also exhibits some FSH activities. Expand
Short and long phases of progesterone secretion during the oestrous cycle of the African elephant (Loxodonta africana).
TLDR
Periovulatory changes in progesterone and LH in sera correlated with external signs of oestrus and mating behaviour, and changing serum progestersone concentrations indicated an oestrous cycle length of 13.3 +/- 1.3 weeks. Expand
Physiological evidence for two sturgeon gonadotrophins in Acipenser transmontanus
TLDR
The gonadotropin releasing hormone analog D-Ala 6 -des-Gly 10 -GnRH ethylamide (GnRHa) was effective in stimulating the release of both gonadotrophins in mature males and preovulatory females, with a maximal response occurring in the spring. Expand
Evolution of gonadotropin structure and function.
TLDR
This chapter describes a flow diagram of the protocol for the fractionation of pituitary hormones, with particular reference to gonadotropins and growth hormone (GH) from various nonmammalian species, and preliminary evidence of chemical similarity among the different species of FSH and of LH. Expand
Stimulation of aromatization of exogenous and endogenous androgens in ovaries of hypophysectomized rats in vivo by follicle-stimulating hormone.
TLDR
It is concluded that FSH and LH regulate ovarian estrogen secretion in vivo by acting at biochemically distinct sites--LH stimulating the synthesis of C19-steroids, which are then converted to estradiol-17beta under specific stimulation by FSH. Expand
Inhibition of follicle-stimulating hormone-induced ovulation by indomethacin in the perfused rat ovary.
TLDR
The data confirm earlier findings that FSH can induce ovulations and show that prostaglandins are involved in this process, and indicate that prostagslandins might be involved in the FSH-induced increase of progesterone levels. Expand
Granulosa cells as hormone targets: the role of biologically active follicle-stimulating hormone in reproduction.
TLDR
The chapter highlights the reception, action, and local synthesis of various growth factors and further explains the paracrine and autocrine roles of these growth factors in the modulation of FSH actions at the granulosa cells. Expand
...
1
2
3
4
5
...