• Publications
  • Influence
Animal model of adenine-induced chronic renal failure in rats.
Long-term feeding of adenine to rats produced metabolic abnormalities resembling chronic renal failure in humans. Among the disturbances produced were azotemia, accumulation of uremic toxins,Expand
Magnesium and Ammonium-Potassium Lithospermates B, the Active Principles Having a Uremia-Preventive Effect from Salvia miltiorrhiza
The active components which exhibit the improving effect on uremic symptoms have been isolated from Salviae miltriorrhizae Radix and characterized as magnesium lithospermate (1) andExpand
Chemical structures and corticosterone secretion-inducing activities of saikosaponins.
The corticosterone secretion-inducing activities of saikosaponins isolated from the roots of Bupleurum falcatum L., their artifact saponins and genuine genins were examined in rats 30 minutes afterExpand
Tannins and Related Compounds. I. Rhubarb (1)
Three new tannin-related compounds (I, II and III), along with lindleyin (IV), (+)-catechin, 3-O-galloyl-(-)-epicatechin, gallic acid, 3, 5, 4'-trihydroxystilbeneExpand
Production of methylguanidine from creatinine via creatol by active oxygen species: analyses of the catabolism in vitro.
The chemical oxidative conversion of creatinine (Cr) into methylguanidine (MG) has been followed by 1H-NMR and HPLC. By using active oxygen species generated by Fenton's reagent (Fe2+ and H2O2) orExpand
Effect of magnesium lithospermate B in rats with sodium-induced hypertension and renal failure.
To evaluate the antihypertensive effect of magnesium lithospermate B isolated from Salviae miltiorrhizae radix, determinations of blood pressure and urinary excretions of sodium, potassium,Expand
Magnesium lithospermate B suppresses the increase of active oxygen in rats after subtotal nephrectomy.
Subtotally nephrectomized rats were found to have decreased activities of superoxide dismutase (SOD) and catalase, and spin trapping with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) showed that theExpand
Ursolic acid inhibits aflatoxin B1-induced mutagenicity in a Salmonella assay system.
An attempt was made to isolate the active component of Eriobotrya japonica, which inhibits aflatoxin B1-induced mutagenicity in the Salmonella assay system. The number of revertants per plate wasExpand