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- Publications
- Influence
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- D. Klionsky, Kotb Abdelmohsen, +2,464 authors S. Zughaier
- Biology, Medicine
- Autophagy
- 18 April 2012
In 2008 we published the first set of guidelines for
standardizing research in autophagy. Since then, research on
this topic has continued to accelerate, and many new scientists
have entered the… Expand
Macromolecular organization of ATP synthase and complex I in whole mitochondria
- K. M. Davies, M. Strauss, +5 authors W. Kühlbrandt
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 11 August 2011
We used electron cryotomography to study the molecular arrangement of large respiratory chain complexes in mitochondria from bovine heart, potato, and three types of fungi. Long rows of ATP synthase… Expand
Mitochondrial quality control: an integrated network of pathways.
- F. Fischer, A. Hamann, H. Osiewacz
- Biology, Medicine
- Trends in biochemical sciences
- 1 July 2012
Mitochondria are organelles of eukaryotic cells with various functions. Best known is their role in energy transduction leading to the formation of ATP. As byproducts of this process, reactive oxygen… Expand
Differential expression of the psbA genes in the cyanobacterium Synechocystis 6803
- A. Mohamed, J. Eriksson, H. Osiewacz, C. Jansson
- Biology, Medicine
- Molecular and General Genetics MGG
- 1 April 1993
The 5′ region and transcription initiation sites of the psbA-2 and psbA-3 genes of Synechocystis 6803 were determined. The otherwise highly homologous genes were shown to diverge significantly in the… Expand
Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors
- S. Gispert, Dajana Parganlija, +17 authors G. Auburger
- Biology, Medicine
- Human molecular genetics
- 12 July 2013
Abstract The caseinolytic peptidase P (CLPP) is conserved from bacteria to humans. In the mitochondrial matrix, it multimerizes and forms a macromolecular proteasome-like cylinder together with the… Expand
Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models
- C. Scheckhuber, N. Erjavec, A. Tinazli, A. Hamann, T. Nyström, H. Osiewacz
- Biology, Medicine
- Nature Cell Biology
- 2007
Ageing of biological systems is accompanied by alterations in mitochondrial morphology, including a transformation from networks and filaments to punctuate units. The significance of these… Expand
Copper homeostasis and aging in the fungal model system Podospora anserina: differential expression of PaCtr3 encoding a copper transporter.
- C. Borghouts, C. Scheckhuber, O. Stephan, H. Osiewacz
- Biology, Medicine
- The international journal of biochemistry & cell…
- 1 November 2002
Lifespan extension of Podospora anserina mutant grisea is caused by a loss-of-function mutation in the nuclear gene Grisea. This gene encodes the copper regulated transcription factor GRISEA recently… Expand
De novo Assembly of a 40 Mb Eukaryotic Genome from Short Sequence Reads: Sordaria macrospora, a Model Organism for Fungal Morphogenesis
- M. Nowrousian, J. Stajich, +15 authors M. Freitag
- Biology, Medicine
- PLoS genetics
- 1 April 2010
Filamentous fungi are of great importance in ecology, agriculture, medicine, and biotechnology. Thus, it is not surprising that genomes for more than 100 filamentous fungi have been sequenced, most… Expand
Guidelines and recommendations on yeast cell death nomenclature
- D. Carmona-Gutierrez, M. A. Bauer, +84 authors F. Madeo
- Biology, Medicine
- Microbial cell
- 1 January 2018
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular… Expand
Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina
- A. Hamann, D. Brust, H. Osiewacz
- Biology, Medicine
- Molecular microbiology
- 1 August 2007
Podospora anserina is a filamentous fungus with a limited lifespan. After a strain‐specific period of growth, cultures turn to senescence and ultimately die. Here we provide evidence that the last… Expand