• Publications
  • Influence
Molecular cloning and characterization of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiology
The results indicate that TTV would be responsible for a part of acute and chronic liver disease of unknown etiology. Expand
A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology.
Results indicate that TTV would be a novel DNA virus with a possible capacity to induce posttransfusion non-A to G hepatitis. Expand
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
These proposals provide the framework by which the HCV databases store and provide access to data on HCV, which will internationally coordinate the assignment of new genotypes and subtypes in the future. Expand
Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food.
Results indicate that inadequately cooked pig liver may transmit HEV to humans. Expand
Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes.
The results indicate that the four major antigenically defined subtypes of envelope polypeptide do not reflect true genotypic variation of HBV and can be induced by an A----G point mutation at nucleotides 365 and 479 in the S gene. Expand
Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources.
HCV types were identical in mother and baby in each of two examples of perinatal transmission, and were also identical in donor and recipient in a case of accidental needle exposure. Expand
Genomic characterization of TT viruses (TTVs) in pigs, cats and dogs and their relatedness with species-specific TTVs in primates and tupaias.
The results indicate that domestic pigs, cats and dogs are naturally infected with species-specific TTVs with small genomic size and suggest a wide distribution of T televisions with extremely divergent genomic sequence and length in animals. Expand
Consensus proposals for classification of the family Hepeviridae
This work proposes a taxonomic scheme in which the family Hepeviridae is divided into the genera Orthohepevirus (all mammalian and avian hepatitis E virus (HEV) isolates) and PiscihepeVirus (cutthroat trout virus), and proposals are made for the designation of genotypes within the human and rat HEVs. Expand
Genetic variability and evolution of hepatitis E virus.
  • H. Okamoto
  • Biology, Medicine
  • Virus research
  • 1 August 2007
Current knowledge on the genomic variability, geographic distribution and zoonotic aspects of Hepevirus as well as the clinical significance of genotype and evolution of HEV are reviewed. Expand
Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and noncoding regions.
TTV strains with extremely high sequence divergence prevailing in healthy individuals and frequent mixed infection with TTV strains of distinct genotypes are indicated. Expand