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Amelioration of hyperalgesia by kinin receptor antagonists or kininogen deficiency in chronic constriction nerve injury in rats
Abstract:Objective: The present study was designed to examine the involvement of bradykinin in thermal and mechanical hyperalgesia induced by chronic constriction nerve injury (CCI) using B1 and B2Expand
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Role of inducible nitric oxide synthase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia.
BACKGROUND AND PURPOSE Bacterial lipopolysaccharide (LPS), an endotoxin, has been reported to induce the expression of inducible isoforms of both nitric oxide synthase (iNOS) and cyclooxygenaseExpand
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Chronic effects of enalapril and amlodipine on cardiac remodeling in cardiomyopathic hamster hearts.
This study examined the effects of long-term treatments with the angiotensin-converting enzyme inhibitor, enalapril, and the calcium antagonist, amlodipine, on the morphologic changes, progressiveExpand
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Neuronal NOS-derived NO plays permissive role in cerebral blood flow response to hypercapnia.
The aim of the present study was to determine whether neuronal nitric oxide synthase (nNOS)-derived nitric oxide (NO) plays a permissive role in the regulation of cerebral blood flow (CBF) responseExpand
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Pravastatin Attenuates Left Ventricular Remodeling and Diastolic Dysfunction in Angiotensin II-Induced Hypertensive Mice
Background: A substantial proportion of patients with heart failure have a normal ejection fraction and diastolic dysfunction. However, there are few data available to guide the therapy of theseExpand
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A diurnal variation of vasoactive intestinal peptide (VIP) mRNA under a daily light-dark cycle in the rat suprachiasmatic nucleus
SummaryWe detected a diurnal change of vasoactive intestinal peptide (VIP) messenger RNA (mRNA) in the rat suprachiasmatic nucleus (SCN) using the in situ hybridization technique combined withExpand
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Effects of low-dose γ-irradiation on the cell cycle duration of barley roots
Abstract This study investigates the effects of 1.0 Gy or less of γ-irradiation on the duration of the cell cycle and its component phases in the root apical meristem of two-rowed barley seedlings.Expand
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Isolation and Activation of Inactive Renin from Human Kidney and Plasma: Plasma and Renal Inactive Renins Have Different Molecular Weights
SUMMARY Inactive renin and active renin from human kidney and human plasma were prepared in highly purified forms by three steps of chromatography on Octyl-Sepharose, Immunoafflnity chromatography,Expand
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Antihypertensive effect of a proteasome inhibitor in DOCA-salt hypertensive rats.
To search for a possible role for vascular proteasome in hypertension, we examined changes in proteasome level in aorta of deoxycorticosterone acetate (DOCA)-salt hypertensive rats and evaluated theExpand
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