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- Publications
- Influence
Treatment of graves' disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation.
- A. Yoshihara, JaedukYoshimura Noh, +11 authors K. Ito
- Medicine
- The Journal of clinical endocrinology and…
- 30 April 2012
BACKGROUND
Several reports have suggested that propylthiouracil (PTU) may be safer than methimazole (MMI) for treating thyrotoxicosis during pregnancy because congenital malformations have been… Expand
Clinical characteristics of 852 patients with subacute thyroiditis before treatment.
- E. Nishihara, H. Ohye, +7 authors A. Miyauchi
- Medicine
- Internal medicine
- 2008
OBJECTIVE
Subacute thyroiditis (SAT) is a transient inflammatory disease of the thyroid. We evaluated the clinical characteristics based on laboratory and imaging studies in patients with SAT before… Expand
Haplotype analysis reveals founder effects of thyroglobulin gene mutations C1058R and C1977S in Japan.
- A. Hishinuma, S. Fukata, +17 authors T. Ieiri
- Biology, Medicine
- The Journal of clinical endocrinology and…
- 1 August 2006
CONTEXT
Thyroglobulin (Tg) mutations were previously believed to be rare, resulting in congenital goitrous hypothyroidism. However, an increasing number of patients with Tg mutations, who are… Expand
Effect of levo-thyroxine replacement on non-high-density lipoprotein cholesterol in hypothyroid patients.
- M. Ito, T. Arishima, +11 authors A. Miyauchi
- Medicine
- The Journal of clinical endocrinology and…
- 1 February 2007
CONTEXT
Recently, non-high-density lipoprotein cholesterol (non-HDL-C), a measure of total cholesterol minus HDL-C, has emerged as a predictor of cardiovascular disease.
OBJECTIVE
We evaluated the… Expand
Serial changes in liver function tests in patients with thyrotoxicosis induced by Graves' disease and painless thyroiditis.
- S. Kubota, N. Amino, +8 authors A. Miyauchi
- Medicine
- Thyroid : official journal of the American…
- 14 March 2008
CONTEXT
When the liver function tests are aggravated after starting antithyroid drugs (ATDs) in Graves' hyperthyroidism, discontinuation of ATDs is generally considered. However, a question arises… Expand
Substituting Potassium Iodide for Methimazole as the Treatment for Graves' Disease During the First Trimester May Reduce the Incidence of Congenital Anomalies: A Retrospective Study at a Single…
- A. Yoshihara, J. Noh, +11 authors K. Ito
- Medicine
- Thyroid : official journal of the American…
- 24 September 2015
BACKGROUND
To control hyperthyroidism due to Graves' disease, antithyroid drugs should be administered. Several studies have shown that exposure to methimazole (MMI) during the first trimester of… Expand
Identification of five novel germline mutations of the MEN1 gene in Japanese multiple endocrine neoplasia type 1 (MEN1) families.
- M. Sato, S. Matsubara, +4 authors J. Takahara
- Medicine, Biology
- Journal of medical genetics
- 1 November 1998
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroid glands, the anterior pituitary, and endocrine pancreas. The MEN1 gene has… Expand
Sporadic congenital hyperthyroidism due to a germline mutation in the thyrotropin receptor gene (Leu 512 Gln) in a Japanese patient.
- E. Nishihara, S. Fukata, +7 authors A. Miyauchi
- Medicine
- Endocrine journal
- 1 December 2006
Constitutively activating thyrotropin receptor (TSHR) germline mutations have been identified as a molecular cause of congenital hyperthyroidism. We here describe a Japanese woman who had presented… Expand
Bacteriostatic and cytolytic activity of purple fluid from the sea hare.
- M. Yamazaki, H. Ohye, J. Kisugi, H. Kamiya
- Biology, Medicine
- Developmental and comparative immunology
- 1 September 1990
A bacteriostatic factor, aplysianin P, was purified from the purple fluid of a sea hare, Aplysia kurodai, as a glycoprotein of 60 K daltons. A cytolytic glycoprotein purified from the purple fluid of… Expand
Acute suppurative thyroiditis after fine-needle aspiration causing thyrotoxicosis.
- E. Nishihara, A. Miyauchi, +6 authors K. Kuma
- Medicine
- Thyroid : official journal of the American…
- 9 November 2005
A case of thyrotoxicosis caused by acute suppurative thyroiditis after repeated fine-needle aspiration (FNA) is described. A 39-year-old woman with atopic dermatitis showed rapid enlargement of a… Expand