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High-resolution solution structure of siamycin II: Novel amphipathic character of a 21-residue peptide that inhibits HIV fusion
The amphipathic nature of siamycin II and siamYcin I suggests that a polar (or apolar) site on the target protein may be masked by the apolar face of the peptide upon peptide/protein complexation. Expand
Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity.
Streptomyces roseiscleroticus L827-7 (ATCC 53903) produced a novel antifungal and antitumor antibiotic, sultriecin. It exhibited in vitro antifungal activity and potent in vivo antitumor activityExpand
Glidobactins D, E, F, G and H; minor components of the antitumor antibiotic glidobactin.
SBT, a new semisynthetic beta-lactamase inhibitor restores and extends the spectrum of ABPC against resistant strains of bacteria, was safe and well tolerated and was highly effective for the treatment of infectious diseases in the pediatric field. Expand
Dynemicins, new antibiotics with the 1,5-diyn-3-ene and anthraquinone subunit. I. Production, isolation and physico-chemical properties.
A novel antibiotic containing the bicyclo[7.3.1]-1,5-diyn-3-ene and 1,4,6-trihydroxyanthraquinone functionalities cured mice from lethal Staphylococcus aureus infection and prolonged survival time of mice inoculated with murine tumors. Expand
Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit.
BBM-928, a new antitumor antibiotic complex. I. Production, isolation, characterization and antitumor activity.
A complex of the antitumor antibiotic BBM-928 was produced by an actinomycete strain No. G455-101. Four components, BBM-928 A, B, C and D, were isolated in crystalline form and characterized. TheyExpand