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Neuroendocrine differentiation correlates with hormone receptor expression and decreased survival in patients with invasive breast carcinoma
TLDR
This work investigated the incidence and clinical significance of NE differentiation in patients with IBC and found that the former is more common than the latter. Expand
The differential expression of TGF-β1, ILK and wnt signaling inducing epithelial to mesenchymal transition in human renal fibrogenesis: an immunohistochemical study.
TLDR
The type II EMT process in humans is thought to be an adaptive response of TECs to chronic injury and is regulated by interconnections of TGF-β/Smad, integrin/integrin-linked kinase (ILK) and wnt/β-catenin signaling pathways. Expand
Glomerular and tubular C4d depositions in IgA nephropathy: relations with histopathology and with albuminuria.
TLDR
Activation of the complement system was involved in renal damage and was identified through deposition of C4d in the glomerulus and tubules and may be associated with functional damage related to glomerular filtration and poor renal outcome. Expand
Expression of Leptin, Leptin Receptor, Adiponectin, and Adiponectin Receptor in Ductal Carcinoma In Situ and Invasive Breast Cancer
TLDR
It is suggested that losses of leptin and ObR expression could beassociated with invasive cancer, whereas high adiponectin and AdipoR expression may be associated with breast cancer invasiveness. Expand
TGF-beta1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstruction.
TLDR
It is suggested that the TGF-beta1 shRNA delays the process of renal fibrosis in UUO mouse model, and would provide a valuable tool to prevent tubulointerstitial fibrosis using RNA interference strategy. Expand
Expression of adiponectin, leptin, and their receptors in ovarian endometrioma.
TLDR
The data suggest that leptin and its receptor are induced in ovarian endometriomas, and that the leptin/ObR system regulates adiponectin gene expression inendometriotic cells. Expand
Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways.
TLDR
The present results show that the ObR is induced in endometriosis, and that leptin stimulates the growth ofendometriotic epithelial cells through the JAK2/STAT3 and ERK pathways. Expand
Malignant Mesothelioma of the Spermatic Cord
TLDR
Despite their rare occurrence in the spermatic cord, MMs need to be suspected, especially in patients with a history of asbestos exposure, especially if they are found to have a contralateral right inguinal mass. Expand
The antifibrotic effect of TGF-beta1 siRNAs in murine model of liver cirrhosis.
TLDR
It is demonstrated that TGF-beta1 siRNAs inhibit TGF -beta1 expression in the murine model of liver cirrhosis and might be a good therapeutic strategy to prevent liver Cirrhosis in human. Expand
Effect of age and stage of endometriosis on ovarian follicular loss during laparoscopic cystectomy for endometrioma
TLDR
The objective was to identify the risk factors associated with inadvertent follicular loss during laparoscopic cystectomy for endometrioma and assess the need for further research on this topic. Expand
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