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Expression of endothelial cell adhesion molecules on heart valves: up‐regulation in degeneration as well as acute endocarditis
Inflammatory cytokines such as interleukin‐1 (IL‐1) and tumour necrosis factor‐alpha (TNF‐α), as well as shear stress, cause endothelial cells (ECs), to undergo not only functional alterations butExpand
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Simvastatin Inhibits Inflammatory Properties of Staphylococcus aureus &agr;-Toxin
Background—Simvastatin, a 3-hydroxy-methylglutaryl coenzyme A reductase inhibitor, has been shown to lower serum cholesterol levels in clinical use. Moreover, statins exert beneficial effects inExpand
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Effect of Medical and Surgical Therapy on Aortic Dissection Evaluated by Transesophageal Echocardiography Implications for Prognosis and Therapy
BackgroundAortic dissection still has a poor prognosis despite progress in therapy. Therefore, this prospective follow-up study was designed to determine whether the degree of communication betweenExpand
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Influence of Mitral Valve Surgery on Tricuspid Incompetence Concomitant with Mitral Valve Disease
Twenty adult patients with predominant mitral valve disease and variable degrees of tricuspid incompetence (TI) were reinvestigated 6-28 months after mitral valve operation. Postoperatively, 10 ofExpand
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Age‐Dependent Changes in the β‐Adrenoceptor—G‐Protein(s)—Adenylyl Cyclase System in Human Right Atrium
Summary: With increasing age, cardiac β-adrenoceptor function decreases. To study possible mechanisms underlying this process, we assessed in right atrial appendages from 52 patients of differentExpand
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Quantification of mitral valve stenosis by three-dimensional transesophageal echocardiography
The aim of this study was the evaluation of the diagnostic potentials of transesophageal 3D-echocardiography in the determination of mitral valve stenosis. 54 patients were investigated byExpand
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Magnetic resonance angiography unmasks reliable target vessels for pedal bypass grafting in patients with diabetes mellitus.
OBJECTIVE The purpose of this study was to evaluate the performance of pedal bypass grafts to foot vessels detected by magnetic resonance angiography (MRA) that were occult in conventionalExpand
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High-Dose ϵ-Aminocaproic Acid Versus Aprotinin: Antifibrinolytic Efficacy in First-Time Coronary Operations
Abstract Background . The antifibrinolytic efficacy of a high-dose regimen of ϵ-aminocaproic acid (ϵ-ACA) was compared with aprotinin in first-time coronary operations. Methods . In a prospective,Expand
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Functional role of cholinoceptors and purinoceptors in human isolated atrial and ventricular heart muscle
1 The effects of cholinergic and purinergic stimulation on action potential, force of contraction and 86Rb efflux were investigated in human atrial and ventricular heart muscle. 2 In atrial heartExpand
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Comparison of Cardiac Troponin I versus T and Creatine Kinase MB after Coronary Artery Bypass Grafting in Patients with and without Perioperative Myocardial Infarction
Background and Purpose:Cardiac troponins have shown to be specific markers of myocardial injury. The aim of this prospective study was to compare patterns and kinetics of troponin I and T afterExpand
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