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Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.
The role of mitochondrial dysfunction in cancer has been a subject of great interest and much ongoing investigation. Although most cancer cells harbor somatic mutations in mitochondrial DNA (mtDNA),… Expand
Pathology of Encapsulating Peritoneal Sclerosis
Pathology findings of encapsulating peritoneal sclerosis (EPS) are reviewed to establish histologic criteria for a diagnosis of EPS. The typical macroscopic finding is a cocoon-like encapsulation of… Expand
Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia
- T. Yasuda, M. Shirakata, +13 authors Y. Yamanashi
- Medicine, Biology
- The Journal of experimental medicine
- 20 December 2004
Dok-1 and Dok-2 are closely related rasGAP-associated docking proteins expressed preferentially in hematopoietic cells. Although they are phosphorylated upon activation of many protein tyrosine… Expand
bor1-1, an Arabidopsis thaliana Mutant That Requires a High Level of Boron
bor1–1 (high boron requiring), an Arabidopsis thaliana mutant that requires a high level of B, was isolated. When the B concentration in the medium was reduced to 3 [mu]M, the expansion of rosette… Expand
Hepatitis B and C Viruses Infection, Lifestyle and Genetic Polymorphisms as Risk Factors for Hepatocellular Carcinoma in Haimen, China
- S. Yu, Xin‐En Huang, +11 authors S. Tokudome
- Biology, Medicine
- Japanese journal of cancer research : Gann
- 1 December 2002
A case‐control study was carried out to investigate the impact of factors including virus infection, aflatoxin B1, microcystins, smoking/drinking and dietary habits as well as genetic polymorphisms… Expand
De novo membranous nephropathy and antibody‐mediated rejection in transplanted kidney
Honda K, Horita S, Toki D, Taneda S, Nitta K, Hattori M, Tanabe K, Teraoka S, Oda H, Yamaguchi Y. De novo membranous nephropathy and antibody‐mediated rejection in transplanted kidney. Clin… Expand
Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia
E2A-hepatic leukemia factor (HLF) is a chimeric protein found in B-lineage acute lymphoblastic leukemia (ALL) with t(17;19). To analyze the leukemogenic process and to create model mice for… Expand
Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.
The AML1/EVI1 chimeric gene is created by the t(3;21)(q26;q22) chromosomal translocation seen in patients with leukemic transformation of myelodysplastic syndrome or blastic crisis of chronic… Expand
Protein-protein interaction panel using mouse full-length cDNAs.
We have developed a novel assay system for systematic analysis of protein-protein interactions (PPIs) that is characteristic of a PCR-mediated rapid sample preparation and a high-throughput assay… Expand
Podocyte and endothelial injury in focal segmental glomerulosclerosis: an ultrastructural analysis
- S. Taneda, K. Honda, M. Ohno, K. Uchida, K. Nitta, H. Oda
- Biology, Medicine
- Virchows Archiv
- 13 August 2015
Podocyte injury contributes to the development of focal segmental glomerulosclerosis (FSGS). Endocapillary hypercellularity, which is one of the pathological characteristics of FSGS, suggests that… Expand